Gene editing that makes target gene modification in the genome by deletion or addition has
revolutionized the era of biomedicine. Clustered regularly interspaced short palindromic …

Bacteria are under immense evolutionary pressure from their viral invaders—
bacteriophages. Bacteria have evolved numerous immune mechanisms, both innate and …

Conspectus The discovery of CRISPR/Cas has revolutionized the field of genome editing.
CRIPSR/Cas components are part of the bacterial immune system and are able to induce …

CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity
which enables prokaryotes to detect any foreign DNA and then destroy it, has gained …

Biomedical researchers have subsequently been inspired the development of new
approaches for precisely changing an organism's genomic DNA in order to investigate …

The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is one of the most devastating outbreaks witnessed in the last 100 years. The outbreak …

The multi‐country outbreak of monkeypox virus (MPXV) infection, while the coronavirus
disease 2019 pandemic is still an ongoing issue, has caused a new challenge. The re …

As genome-editing nucleases move towards broader clinical applications, the need to
define the limits of their specificity and efficiency increases. A variety of approaches for …

The fast-developing synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …