Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder. It is
characterized by the accumulation of α-Synuclein aggregates and the degeneration of …

Autophagy is a self-digestion process in cells that can maintain energy homeostasis under
normal circumstances. However, misfolded proteins, damaged mitochondria and other …

Circular RNAs (circRNAs) are a type of single-stranded RNA molecules forming a covalently
closed, continuous structure, lacking 5′-3′ polarity and polyadenylated tails. Recent …

As a multikinase inhibitor, sorafenib is commonly used to treat patients with advanced
hepatocellular carcinoma (HCC), however, acquired resistance to sorafenib is a major …

Circular RNAs (circRNAs) are the newly uncovered class of non-coding RNAs being
cognized as profound regulators of gene expression in developmental and disease biology …

Traumatic brain injury (TBI) is one of the most well-known causes of neurological impairment
and disability in the world. The Forkhead Box class O (FOXO) 3a is a transcription factor that …

FOXO3a (forkhead box transcription factor 3a) is involved in regulating multiple biological
processes in cancer cells. BNIP3 (Bcl-2/adenovirus E1B 19-kDa-interacting protein 3) is a …

Autophagy is an essential catabolic process that orchestrates cellular homeostasis and
plays dual roles in tumor promotion and suppression. However, the mechanism by which …

Background Research around the weedkiller Roundup is among the most contentious of the
twenty-first century. Scientists have provided inconclusive evidence that the weedkiller …

Enhancer RNAs (eRNAs) transcribed from distal active enhancers serve as key regulators in
gene transcriptional regulation. The accumulation of eRNAs from multiple sequencing …