Innate and innate-like effector lymphocytes in health and disease

L Van Kaer, JL Postoak, W Song… - The Journal of Immunology, 2022 - journals.aai.org
Lymphocytes can be functionally partitioned into subsets belonging to the innate or adaptive
arms of the immune system. Subsets of innate and innate-like lymphocytes may or may not …

Emerging insights into the impact of air pollution on immune-mediated asthma pathogenesis

JA Tuazon, B Kilburg-Basnyat, LM Oldfield… - Current allergy and …, 2022 - Springer
Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice

N Shrestha, P Chaturvedi, X Zhu, MJ Dee… - Aging …, 2023 - Wiley Online Library
Accumulation of senescent cells (SNCs) with a senescence‐associated secretory phenotype
(SASP) has been implicated as a major source of chronic sterile inflammation leading to …

Two‐year results of tapered dupilumab for CRSwNP demonstrates enduring efficacy established in the first 6 months

RJL van der Lans, JJ Otten, GFJPM Adriaensen… - Allergy, 2023 - Wiley Online Library
Background Dupilumab is an anti‐T2‐inflammatory biological registered for chronic
rhinosinusitis (CRS) with nasal polyps (CRSwNP), indicated by integrated CRS‐care …

[HTML][HTML] Molecular and pathophysiological links between metabolic disorders and inflammatory bowel diseases

CK Hyun - International journal of molecular sciences, 2021 - mdpi.com
Despite considerable epidemiological evidence indicating comorbidity between metabolic
disorders, such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease, and …

Alarmins and innate lymphoid cells 2 activation: A common pathogenetic link connecting respiratory syncytial virus bronchiolitis and later wheezing/asthma?

GA Rossi, S Ballarini, P Salvati… - Pediatric allergy and …, 2022 - Wiley Online Library
Severe respiratory syncytial virus (RSV) infection in infancy is associated with increased risk
of recurrent wheezing in childhood. Both acute and long‐term alterations in airway functions …

Vagus nerve-mediated intestinal immune regulation: therapeutic implications of inflammatory bowel diseases

Y Mikami, J Tsunoda, H Kiyohara… - International …, 2022 - academic.oup.com
The pathophysiology of inflammatory bowel diseases (IBDs) involves immunological,
genetic and environmental factors. Through its ability to sense environmental stimuli, the …

[HTML][HTML] Lymphoid Tissue inducer (LTi) cell ontogeny and functioning in embryo and adult

SA van de Pavert - biomedical journal, 2021 - Elsevier
Abstract Innate Lymphoid Cells (ILC) are involved in homeostasis and immunity. Their
dynamic differentiation and characterization depend on their tissue of residency and is …

Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis

Y Wang, L Lifshitz, NJ Silverstein, E Mintzer… - The EMBO …, 2023 - embopress.org
Innate lymphoid cells (ILCs) are a diverse population of cells that include NK cells and
contribute to tissue homeostasis and repair, inflammation, and provide protection from …

[HTML][HTML] Innate lymphoid cells—Underexplored guardians of immunity

I Tsymala, K Kuchler - PLoS Pathogens, 2023 - journals.plos.org
Innate lymphoid cells (ILCs) show remarkable plasticity and influence immunity as early
sensors of pathogenic cues [1–4]. The general term “ILC” describes innate immune cells that …