Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

Cryptococcosis

JR Perfect, A Casadevall - Infectious Disease Clinics, 2002 - id.theclinics.com
Cryptococcus neoformans strains classically have been grouped into two varieties that
included five serotypes known as C. neoformans variety neoformans (serotypes A, D, and …

[图书][B] Cryptococcus neoformans

A Casadevall, JR Perfect - 1998 - Citeseer
MATERIALS AND METHODS Strains and media. C. neoformans var. grubii strains H99 (70),
KN99a (55), KN99 (55), KN99aNAT, and KN99NAT were maintained at 80 C. Cultures were …

Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages

JN Steenbergen, HA Shuman… - Proceedings of the …, 2001 - National Acad Sciences
Cryptococcus neoformans (Cn) is a soil fungus that causes life-threatening meningitis in
immunocompromised patients and is a facultative intracellular pathogen capable of …

[HTML][HTML] Cryptococcal cell morphology affects host cell interactions and pathogenicity

LH Okagaki, AK Strain, JN Nielsen, C Charlier… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …

Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions

DL Oliveira, CG Freire-de-Lima… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

[HTML][HTML] Expulsion of live pathogenic yeast by macrophages

H Ma, JE Croudace, DA Lammas, RC May - Current Biology, 2006 - cell.com
Phagocytic cells, such as neutrophils and macrophages, perform a critical role in protecting
organisms from infection by engulfing and destroying invading microbes [1]. Although some …

Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide …

SC Tucker, A Casadevall - Proceedings of the National …, 2002 - National Acad Sciences
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Cryptococcal interactions with the host immune system

K Voelz, RC May - Eukaryotic cell, 2010 - Am Soc Microbiol
Opportunistic pathogens have become of increasing medical importance over the last
decade due to the AIDS pandemic. Not only is cryptococcosis the fourth-most-common fatal …