The NOD‐like receptor family pyrin domain containing 6 (NLRP6), a member of the NOD‐
like receptor (NLR) family, acts as a cytosolic innate immune sensor that recognizes microbe …

In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

There is increasing evidence that gut microbiome perturbations, also known as dysbiosis,
can influence colorectal cancer development. To understand the mechanisms by which the …

NACHT, LRR (leucine-rich repeat), and PYD (pyrin domain) domain-containing 6 (Nlrp6) is
a member of the NLR (nucleotide-oligomerization domain-like receptor) family that patrols …

Acute graft‐versus‐host disease (GVHD) remains a major complication after allogeneic
haematopoietic stem cell transplantation (allo‐HSCT). The emergence of different immuno …

The nucleotide-binding oligomerization and leucine-rich repeat receptor (NLR) protein
family consists of important immune sensors that form inflammasomes, a cytosolic multi …

The orphan nuclear receptor ESRRA (estrogen related receptor alpha) is critical in
mitochondrial biogenesis and macroautophagy/autophagy function; however, the roles of …

The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

The development of human mesenchymal stromal/stem cell (MSC)-based therapy has
focused on exploring biological nanoparticles secreted from MSCs. There is emerging …

Abstract The PI3K/AKT pathway plays an essential role in tumour development. NOD-like
receptors (NLRs) regulate innate immunity and are implicated in cancer, but whether they …