Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …

The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

Chronic inflammation is a well-known risk factor for cancer. Proinflammatory mediators such
as prostaglandin E2 (PGE2) promote colorectal tumor growth by stimulating angiogenesis …

AIMS: Inducible cyclooxygenase (COX-2) has been implicated in the process of
inflammation and carcinogenesis. Chamomile has long been used in traditional medicine for …

Esophageal adenocarcinoma is preceded by the development of reflux-related intestinal
metaplasia or Barrett esophagus, which is a response to inflammation of the esophageal …

Purpose: Recent studies have shown that cyclooxygenase (Cox)-2 may be involved in
colorectal carcinogenesis. We aimed to determine whether Cox-2 expression in itself can …

Colorectal cancer is the second leading cause of mortality in the United States. In the United
States, the cumulative lifetime risk of developing colorectal cancer for both men and women …

Background & Aims: Overexpression of cyclooxygenase-2 (COX-2) is implicated in many
steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 …

Abstract Cyclooxygenase-2 (COX-2) is an inducible enzyme that regulates prostaglandin
synthesis and is overexpressed at sites of inflammation and in several epithelial cancers …