Squamous cell carcinoma of the hypopharynx represents a distinct clinical entity. Most
patients present with significant comorbidities and advanced‐stage disease. The overall …

Despite substantial improvements in head and neck squamous cell carcinoma (HNSCC)
treatment, the major obstacle to long‐term survival remains disease recurrence. Salvage …

Chemoradiotherapy has emerged as a gold standard in advanced squamous cell carcinoma
of the head and neck (SCCHN). Because 50% of advanced stage patients relapse after …

It has been documented previously that defects in the generation of C18-ceramide, a
product of ceramide synthase 1 (CerS1), also known as longevity assurance gene 1 …

Objective Salvage surgery in recurrent SCCHN is associated with poor outcomes. This study
aimed to better identify suitable surgical candidates and those at high risk of new …

Our objective was to evaluate recurrence patterns of hypopharyngeal and laryngeal
carcinoma after chemoradiation and options for salvage surgery, with special emphasis on …

Purpose Salvage surgery for recurrent advanced stage head and neck squamous cell
carcinoma (HNSCC) is known to result in poor prognosis. As there are only small and …

Background: Head and neck cancers are prevalent in Thailand, in particular in the southern
region of the country. However, survival with a large data set has not been reported. The …

The therapeutic options and prognosis for recurrent squamous cell carcinoma of the upper
aerodigestive tract vary greatly depending on site, extent of disease, and previous treatment …

Background Patients undergoing salvage laryngectomy are predisposed to radiation-
induced hypothyroidism and impaired wound healing secondary to the tissue effects of prior …