High-fat diet related lung fibrosis-epigenetic regulation matters

J Yang, C Liang, L Liu, L Wang, G Yu - Biomolecules, 2023 - mdpi.com
Pulmonary fibrosis (PF) is an interstitial lung disease characterized by the destruction of the
pulmonary parenchyma caused by excessive extracellular matrix deposition. Despite the …

[HTML][HTML] The melatonergic pathway and its interactions in modulating respiratory system disorders

G Mazzoccoli, I Kvetnoy, E Mironova… - Biomedicine & …, 2021 - Elsevier
Melatonin is a key intracellular neuroimmune-endocrine regulator and coordinator of
multiple complex and interrelated biological processes. The main functions of melatonin …

Mitochondrial dysfunction in lung resident mesenchymal stem cells from idiopathic pulmonary fibrosis patients

J Mercader-Barceló, A Martín-Medina, J Truyols-Vives… - Cells, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is characterized by an aberrant repair response with
uncontrolled turnover of extracellular matrix involving mesenchymal cell phenotypes, where …

Qi-Long-Tian capsule alleviates pulmonary fibrosis development by modulating inflammatory response and gut microbiota

Q Zhang, T Luo, D Yuan, J Liu, Y Fu, J Yuan - Functional & integrative …, 2023 - Springer
Pulmonary fibrosis (PF) is a chronic, progressive, and fibrotic interstitial lung disease with a
high mortality rate. Qi-Long-Tian (QLT) capsule is an herbal formula with great potential for …

Lifestyle, genetic susceptibility, and the risk of idiopathic pulmonary fibrosis: a large prospective cohort study

Y Ma, F Cui, D Li, J Wang, L Tang, J Xie, Y Hu, Y Tian - Chest, 2023 - Elsevier
Background Lifestyle is an important contributor of age-related chronic disease, but the
association between lifestyle and the risk of idiopathic pulmonary fibrosis (IPF) remains …

Polydatin alleviates bleomycin‐induced pulmonary fibrosis and alters the gut microbiota in a mouse model

J Yang, X Shi, R Gao, L Fan, R Chen… - Journal of Cellular …, 2023 - Wiley Online Library
To investigate the effect and mechanism of polydatin on bleomycin (BLM)‐induced
pulmonary fibrosis in a mouse model. The lung fibrosis model was induced by BLM. The …

Cellular and molecular control of lipid metabolism in idiopathic pulmonary fibrosis: clinical application of the lysophosphatidic acid pathway

Y Nakamura, Y Shimizu - Cells, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a representative disease that causes fibrosis of the
lungs. Its pathogenesis is thought to be characterized by sustained injury to alveolar …

Dietary phytoestrogens ameliorate hydrochloric acid-induced chronic lung injury and pulmonary fibrosis in mice

P Solopov, RML Colunga Biancatelli, C Dimitropoulou… - Nutrients, 2021 - mdpi.com
We previously reported that female mice exhibit protection against chemically induced
pulmonary fibrosis and suggested a potential role of estrogen. Phytoestrogens act, at least in …

Edible bird's nest alleviates pneumonia caused by tobacco smoke inhalation through the TNFR1/NF‐κB/NLRP3 pathway

R Bi, D Zhang, R Quan, X Lin, W Zhang… - Food Science & …, 2024 - Wiley Online Library
Exposure to cigarette smoke directly damages the lungs and causes lung inflammation. The
anti‐inflammatory properties of edible bird's nest (EBN) have been reported. We aimed to …

Precision medicine in idiopathic pulmonary fibrosis therapy: From translational research to patient-centered care

KM Antoniou, E Tsitoura, E Vasarmidi… - Current Opinion in …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic chronic lung disease
affecting predominantly older adults, with a history of smoking. The current model of disease …