Replication factor C (RFC) family is a complex comprised of the RFC1, RFC2, RFC3, RFC4,
and RFC5 subunits, which acts as a primer recognition factor for DNA polymerase. It is …

Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality. The abnormal
expression of genes is significantly related to the occurrence of HCC. The aim of this study …

Introduction Although some circRNAs have been found to regulate the progression of
malignancies, their functions and coupled molecular mechanisms are still unclear. In our …

An approach for safely delivering AgNPs to cancer cells and the evaluation of the affected
cellular mechanism are presented. The use of mesoporous silica nanoparticles (MSNs) as …

Objective Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that
originates from the squamous cells. The role of the replication factor C subunit 3 (RFC3) in …

Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related
death worldwide. We showed previously that calcium/calmodulin-dependent protein kinase …

Triple-negative breast cancer (TNBC) was regarded as the most aggressive and mortal
subtype of breast cancer (BC) since the molecular subtype system has been established …

Extensive studies on tumor suppressor genes (TSGs) are helpful to understand the
pathogenesis of cancer and design effective treatments. However, identifying TSGs using …

Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

Colorectal cancer (CRC) ranks among the most prevalent cancers globally, with its
incidence closely tied to DNA damage. The Replication Factor C (RFC) complexes …