Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Alteration in the density and composition of extracellular matrix (ECM) occurs in tumors. The
alterations toward both stiffness and degradation are contributed to tumor growth and …

The ferroptosis effect has been illuminated with a clear Fenton reaction mechanism that
converts endogenous hydrogen peroxide (H2O2) into highly oxidative hydroxyl radicals …

Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

External stimuli-responsive nanomedicine with desirable repetitive on-demand drug release
character is postulated to greatly accommodate patients' flexible medication regime. To this …

Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

Hepatocellular carcinoma (HCC) has been known as the second common leading cancer
worldwide, as it responds poorly to both chemotherapy and medication. Triptolide (TP), a …

Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …