[HTML][HTML] Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

F Aubry, S Jacobs, M Darmuzey, S Lequime… - Nature …, 2021 - nature.com
The global emergence of Zika virus (ZIKV) revealed the unprecedented ability for a mosquito-
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …

[HTML][HTML] An overview of Zika virus genotypes and their infectivity

LC Bernardo-Menezes, A Agrelli… - Revista da Sociedade …, 2022 - SciELO Brasil
Zika virus (ZIKV) is an enveloped, single-stranded RNA arbovirus belonging to the genus
Flavivirus. It was first isolated from a sentinel monkey in Uganda in 1947. More recently …

Using macaques to address critical questions in Zika virus research

DM Dudley, MT Aliota, EL Mohr… - Annual review of …, 2019 - annualreviews.org
Zika virus (ZIKV) and nonhuman primates have been inextricably linked since the virus was
first discovered in a sentinel rhesus macaque in Uganda in 1947. Soon after ZIKV was …

[HTML][HTML] Astrocytes derived from neural progenitor cells are susceptible to Zika virus infection

EI Rubio-Hernández, M Comas-García… - PLoS …, 2023 - journals.plos.org
Zika virus (ZIKV) was first isolated in 1947. From its isolation until 2007, symptoms of ZIKV-
caused disease were limited (eg, fever, hives, and headache); however, during the epidemic …

[HTML][HTML] Asian Zika virus isolate significantly changes the transcriptional profile and alternative RNA splicing events in a neuroblastoma cell line

G Bonenfant, R Meng, C Shotwell, P Badu, AF Payne… - Viruses, 2020 - mdpi.com
The alternative splicing of pre-mRNAs expands a single genetic blueprint to encode
multiple, functionally diverse protein isoforms. Viruses have previously been shown to …

Shared molecular signatures across zika virus infection and multiple sclerosis highlight AP-1 transcription factor as a potential player in post-ZIKV MS-like phenotypes

EV da Silva, FL Fontes-Dantas, TV Dantas… - Molecular …, 2023 - Springer
Zika virus (ZIKV) is an arbovirus of the Flaviviridae genus that has rapidly disseminated from
across the Pacific to the Americas. Robust evidence has indicated a crucial role of ZIKV in …

Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses

W Chen, SS Foo, E Hong, C Wu, WS Lee, SA Lee… - Nature …, 2021 - nature.com
The most frequent fetal birth defect associated with prenatal Zika virus (ZIKV) infection is
brain calcification, which in turn may potentially affect neurological development in infants …

Temperate conditions limit zika virus genome replication

B Tesla, JS Powers, Y Barnes, S Lakhani… - Journal of …, 2022 - Am Soc Microbiol
Zika virus is a mosquito-borne flavivirus known to cause severe birth defects and
neuroimmunological disorders. We have previously demonstrated that mosquito …

[HTML][HTML] Network of interactions between ZIKA virus non-structural proteins and human host proteins

VA Golubeva, TC Nepomuceno, G de Gregoriis… - Cells, 2020 - mdpi.com
The Zika virus (ZIKV) is a mosquito-borne Flavivirus and can be transmitted through an
infected mosquito bite or through human-to-human interaction by sexual activity, blood …

Patterns of herpes simplex virus 1 infection in neural progenitor cells

W Zheng, AM Klammer, JN Naciri, J Yeung… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT Herpes simplex virus 1 (HSV-1) can induce damage in brain regions that
include the hippocampus and associated limbic structures. These neurogenic niches are …