Gallic acid (GA), also known as 3, 4, 5-trihydroxybenzoic acid, is a natural secondary
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

In rheumatoid arthritis (RA) pathogenesis, activated RA fibroblast-like synoviocytes (RA-
FLSs) exhibit similar proliferative features as tumor cells and subsequent erosion to cartilage …

Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic
disruption that may be therapeutically targetable. Among them, glucose metabolism and …

Objective. Fibroblast-like synoviocytes (FLSs) are critical for promoting joint damage in
rheumatoid arthritis (RA). N6-methyladenosine (m6A) modification plays key roles in various …

Background The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by
neovascularization, immune cell infiltration, and synovial hyperplasia, which leads to …

Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …

Abstract Ethnopharmacological relevance Ershiwuwei Lvxue Pill (ELP, མགྲིན་ མཚལ་ ཉེར་
ལྔ།), a traditional Tibetan medicine preparation, has been used hundreds of years for the …

Introduction The synovial membrane is the main site of inflammation in rheumatoid arthritis
(RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions …