[HTML][HTML] Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
J Bai, Y Zhang, C Tang, Y Hou, X Ai, X Chen… - Biomedicine & …, 2021 - Elsevier
Gallic acid (GA), also known as 3, 4, 5-trihydroxybenzoic acid, is a natural secondary
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …
[HTML][HTML] Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs
W Jing, C Liu, C Su, L Liu, P Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
[HTML][HTML] A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-α induced inflammatory cytokine production of synovial fibroblasts from …
H Du, X Zhang, Y Zeng, X Huang, H Chen… - Frontiers in …, 2019 - frontiersin.org
In rheumatoid arthritis (RA) pathogenesis, activated RA fibroblast-like synoviocytes (RA-
FLSs) exhibit similar proliferative features as tumor cells and subsequent erosion to cartilage …
FLSs) exhibit similar proliferative features as tumor cells and subsequent erosion to cartilage …
[HTML][HTML] Fibroblast-like synoviocytes glucose metabolism as a therapeutic target in rheumatoid arthritis
PG De Oliveira, M Farinon, E Sanchez-Lopez… - Frontiers in …, 2019 - frontiersin.org
Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic
disruption that may be therapeutically targetable. Among them, glucose metabolism and …
disruption that may be therapeutically targetable. Among them, glucose metabolism and …
[PDF][PDF] ALKBH5-mediated RNA m (6) A methylation regulates the migration, invasion and proliferation of rheumatoid fibroblast-like synoviocytes
Y Kuang, R Li, J Wang, S Xu, Q Qiu, S Lin… - Arthritis …, 2023 - researchgate.net
Objective. Fibroblast-like synoviocytes (FLSs) are critical for promoting joint damage in
rheumatoid arthritis (RA). N6-methyladenosine (m6A) modification plays key roles in various …
rheumatoid arthritis (RA). N6-methyladenosine (m6A) modification plays key roles in various …
Punicalagin inhibited inflammation and migration of fibroblast-like synoviocytes through NF-κB pathway in the experimental study of rheumatoid arthritis
M Huang, K Wu, S Zeng, W Liu, T Cui… - Journal of …, 2021 - Taylor & Francis
Background The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …
the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural …
Metabolites as drivers and targets in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by
neovascularization, immune cell infiltration, and synovial hyperplasia, which leads to …
neovascularization, immune cell infiltration, and synovial hyperplasia, which leads to …
[HTML][HTML] Tanshinone IIA suppresses proliferation and inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients induced by TNF-α and …
H Du, Y Wang, Y Zeng, X Huang, D Liu, L Ye… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …
Tibetan medicine Ershiwuwei Lvxue Pill attenuates collagen-induced arthritis via inhibition of JAK2/STAT3 signaling pathway
C Liu, Q Zhao, L Zhong, Q Li, R Li, S Li, Y Li, N Li… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Ershiwuwei Lvxue Pill (ELP, མགྲིན་ མཚལ་ ཉེར་
ལྔ།), a traditional Tibetan medicine preparation, has been used hundreds of years for the …
ལྔ།), a traditional Tibetan medicine preparation, has been used hundreds of years for the …
[HTML][HTML] Differential effect of lactate on synovial fibroblast and macrophage effector functions
V Pucino, M Nefla, V Gauthier, G Alsaleh… - Frontiers in …, 2023 - frontiersin.org
Introduction The synovial membrane is the main site of inflammation in rheumatoid arthritis
(RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions …
(RA). Here several subsets of fibroblasts and macrophages, with distinct effector functions …