Rheumatoid arthritis (RA) is an enduring autoimmune inflammatory condition distinguished
by continual joint inflammation, hyperplasia of the synovium, erosion of bone, and …

Fibroblast-like synoviocytes (FLS) plays an important role in synovial inflammation and joint
damage in rheumatoid arthritis (RA). As the most abundant mRNA modification, N6 …

Objective: Rheumatoid arthritis (RA), as a chronic autoimmune disorder, seriously threatens
human health. However, no study has thoroughly illustrated the etiology of RA. The present …

Rheumatoid arthritis (RA) is an autoimmune disease, which can lead to joint inflammation
and progressive joint destruction. Kruppel-like factor 7 (KLF7) is the member of KLF family …

Using next-generation sequencing to decipher the molecular mechanisms underlying
aberrant rheumatoid arthritis synovial fibroblasts (RASF) activation, we performed …

Objective Aggressive phenotype and abnormal glycolytic metabolism of fibroblast-like
synoviocytes (FLSs) are essential to joint inflammation and damage in rheumatoid arthritis …

骨关节炎(Osteoarthritis, OA) 是一种普遍影响中老年人群的慢性炎性疾病,
其典型表现为软骨退行性变, 关节炎症以及功能受损. 面对目前缺乏有效治疗手段的现状 …

Background The interaction of small molecules with direct targets constitutes the molecular
initiation events of drug efficacy and toxicity. Aconitine, an active compound of the Aconitum …

Hintergrund Energie ist die Währung des Lebens. Der systemische und zelluläre
Energiestoffwechsel spielen eine wesentliche Rolle für die Energieversorgung des …

Rheumatoid arthritis is a classic autoimmune disease, the pathogenesis of which is closely
linked to the auto-reactivity of immune cells and joint inflammation. Three cell types, namely …