Acetylcholine is an essential excitatory neurotransmitter in the central nervous system and
undertakes a vital role in cognitive function. Consequently, there is ample evidence to …

Synaptic plasticity in the mammalian central nervous system has been the subject of intense
investigation for the past four decades. Long-term potentiation (LTP), a major reflection of …

Tau pathology is encountered in many neurodegenerative disorders known as tauopathies,
including Alzheimer's disease. Physical activity is a lifestyle factor affecting processes crucial …

Abstract The Cholinergic and GABAergic fibers of the medial septal/diagonal band of Broca
(MS/DB) area project to the hippocampus and constitute the septo-hippocampal pathway …

Both acetylcholine (ACh) and theta oscillations are important for learning and memory, but
the dynamic interaction between these two processes remains unclear. Recent advances in …

BACKGROUND AND AIM: The anatomical connections of septum and hippocampus and the
influence of cholinergic and glutamatergic projections in these sites have been reported. In …

Studies on the effect of scopolamine on memory are abundant but so far only regulation of
the muscarinic receptor (M1) has been reported. We hypothesized that levels of other …

Due to the improvement of medical level, life expectancy increased. But the increased
incidence of cognitive disorders is an emerging social problem. Current drugs for dementia …

Although the incidence rate of dementia is rapidly growing in the aged population,
therapeutic and preventive reagents are still suboptimal. Various model systems are used …

Recently, our research team reported the anti-amnesic potential of desalted-hydroethanolic
extracts of Salicornia europaea L.(SE-EE). In this study, we performed bioactivity-guided …