[HTML][HTML] Selection strategy of dextran sulfate sodium-induced acute or chronic colitis mouse models based on gut microbial profile

HM Xu, HL Huang, YD Liu, JQ Zhu, YL Zhou, HT Chen… - BMC microbiology, 2021 - Springer
Background Dextran sulfate sodium (DSS) replicates ulcerative colitis (UC)-like colitis in
murine models. However, the microbial characteristics of DSS-triggered colitis require …

Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes

C Sorini, I Cosorich, M Lo Conte… - Proceedings of the …, 2019 - National Acad Sciences
Low-grade intestinal inflammation and alterations of gut barrier integrity are found in patients
affected by extraintestinal autoimmune diseases such as type 1 diabetes (T1D), but a direct …

[HTML][HTML] Potential role of fecal microbiota from patients with slow transit constipation in the regulation of gastrointestinal motility

X Ge, W Zhao, C Ding, H Tian, L Xu, H Wang, L Ni… - Scientific reports, 2017 - nature.com
The gut microbiota is involved in various physiological functions, and disturbances in the
host-microbiome have been proven to contribute to the dysfunction of gut; however, whether …

Association between intestinal microbiota and inflammatory bowel disease

Y Zhang, X Si, L Yang, H Wang… - Animal Models and …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative
colitis (UC), has emerged as a global disease with high incidence, long duration …

[HTML][HTML] Key role of gut microbiota in anhedonia-like phenotype in rodents with neuropathic pain

C Yang, X Fang, G Zhan, N Huang, S Li, J Bi… - Translational …, 2019 - nature.com
Patients with chronic neuropathic pain frequently suffer from symptoms of anhedonia, which
is a core symptom of depression. Accumulating studies suggest that gut microbiota may play …

[HTML][HTML] Effects of fish n-3 PUFAs on intestinal microbiota and immune system

C Parolini - Marine drugs, 2019 - mdpi.com
Studies over several decades have documented the beneficial actions of n-3
polyunsaturated fatty acids (PUFAs), which are plentiful in fish oil, in different disease states …

[HTML][HTML] Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome

M Honda, BGJ Surewaard, M Watanabe… - Nature …, 2020 - nature.com
While the ontogeny and recruitment of the intestinal monocyte/macrophage lineage has
been studied extensively, their precise localization and function has been overlooked. Here …

[HTML][HTML] Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

G Zhan, N Yang, S Li, N Huang, X Fang… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Alzheimer's disease is characterized by cognitive dysfunction and aging is an important
predisposing factor; however, the pathological and therapeutic mechanisms are not fully …

[HTML][HTML] Dietary fructose alters the composition, localization, and metabolism of gut microbiota in association with worsening colitis

DC Montrose, R Nishiguchi, S Basu, HA Staab… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The incidence of inflammatory bowel diseases has increased over the
last half century, suggesting a role for dietary factors. Fructose consumption has increased in …

[HTML][HTML] Disturbances of the gut microbiota and microbiota-derived metabolites in inflammatory bowel disease

Y Hu, Z Chen, C Xu, S Kan, D Chen - Nutrients, 2022 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is characterized as a chronic and recurrent inflammatory disease whose pathogenesis …