Vitexin protects against dextran sodium sulfate-induced colitis in mice and its potential mechanisms

J Zhang, F Liang, Z Chen, Y Chen, J Yuan… - Journal of Agricultural …, 2022 - ACS Publications
Vitexin, one of the major active components in hawthorn, has been shown to possess
multiple pharmacological activities. Here, we sought to investigate the effect of vitexin on an …

Differential protective effect of resveratrol and its microbial metabolites on intestinal barrier dysfunction is mediated by the AMPK pathway

B Zhang, Y Zhang, X Liu, J Yin, X Li… - Journal of Agricultural …, 2022 - ACS Publications
The effectiveness of resveratrol (RES) on intestinal barrier dysfunction and colitis has been
extensively studied. However, the specific effects of its microbial metabolites on gut barrier …

Sleep deprivation and gut microbiota dysbiosis: current understandings and implications

J Sun, D Fang, Z Wang, Y Liu - International Journal of Molecular …, 2023 - mdpi.com
Gut microbiota comprises the microbial communities inhabiting our gastrointestinal (GI)
tracts. Accordingly, these complex communities play a fundamental role in many host …

Sucralose promotes colitis-associated colorectal cancer risk in a murine model along with changes in microbiota

X Li, Y Liu, Y Wang, X Li, X Liu, M Guo, Y Tan… - Frontiers in …, 2020 - frontiersin.org
Sucralose is a calorie-free high-intensity artificial sweetener that is widely used in thousands
of foods and beverages all over the world. Although it was initially regarded as a safe, inert …

[HTML][HTML] Manipulation of gut microbiota as a key target for crohn's disease

R Rashed, R Valcheva, LA Dieleman - Frontiers in Medicine, 2022 - frontiersin.org
Crohn's disease (CD) is an inflammatory bowel disease (IBD) sub-type characterized by
transmural chronic inflammation of the gastrointestinal tract. Research indicates a complex …

Initial gut microbiota structure affects sensitivity to DSS-induced colitis in a mouse model

M Li, Y Wu, Y Hu, L Zhao, C Zhang - Science China Life Sciences, 2018 - Springer
The dextran sulfate sodium (DSS)-induced colitis model is a widely applied mouse model,
but controversial results have been obtained from experiments using the same mouse strain …

[HTML][HTML] Development of severe colitis is associated with lung inflammation and pathology

AL Raftery, CA O'Brien, NL Harris, E Tsantikos… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are
chronic relapsing diseases that affect the gastrointestinal tract, most commonly the colon. A …

Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice

P Deol, P Ruegger, GD Logan, A Shawki, J Li… - Gut …, 2023 - Taylor & Francis
Inflammatory bowel disease (IBD) is a multifactorial disease with increasing incidence in the
US suggesting that environmental factors, including diet, are involved. It has been …

Immunoglobulin A, an active liaison for host-microbiota homeostasis

AA Abokor, GH McDaniel, RM Golonka, C Campbell… - Microorganisms, 2021 - mdpi.com
Mucosal surfaces in the gastrointestinal tract are continually exposed to native, commensal
antigens and susceptible to foreign, infectious antigens. Immunoglobulin A (IgA) provides …

Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota

SM Yee, H Choi, JE Seon, YJ Ban, MJ Kim, JE Seo… - Scientific Reports, 2023 - nature.com
Axl is a tyrosine kinase receptor, a negative regulator for innate immune responses and
inflammatory bowel disease (IBD). The gut microbiota regulates intestinal immune …