Epithelial wound healing in inflammatory bowel diseases: the next therapeutic frontier

CY Liu, CM Cham, EB Chang - Translational Research, 2021 - Elsevier
Patients with one of the many chronic inflammatory disorders broadly classified as
inflammatory bowel disease (IBD) now have a diverse set of immunomodulatory therapies at …

[HTML][HTML] Abnormal gut microbiota composition contributes to cognitive dysfunction in streptozotocin-induced diabetic mice

F Yu, W Han, G Zhan, S Li, S Xiang, B Zhu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Both diabetes and Alzheimer's disease are age-related disorders, and numerous studies
have demonstrated that patients with diabetes are at an increased risk of cognitive …

[HTML][HTML] Preserved egg white alleviates DSS-induced colitis in mice through the reduction of oxidative stress, modulation of infl ammatory cytokines, NF-κB, MAPK and …

L Li, N Qiu, Y Meng, C Wang, Y Mine, R Keast… - Food Science and …, 2023 - Elsevier
Traditional Chinese preserved egg products have exhibited some anti-inflammatory effects,
but their mechanisms of action remain unknown. This study aimed to investigate the anti …

Loss of microRNA-21 influences the gut microbiota, causing reduced susceptibility in a murine model of colitis

DGW Johnston, MA Williams, CA Thaiss… - Journal of Crohn's …, 2018 - academic.oup.com
Background and Aims microRNAs regulate gene expression and influence the
pathogenesis of human diseases. The present study investigated the role of microRNA-21 …

Fucose ameliorate intestinal inflammation through modulating the crosstalk between bile acids and gut microbiota in a chronic colitis murine model

J Ke, Y Li, C Han, R He, R Lin, W Qian… - Inflammatory bowel …, 2020 - academic.oup.com
Background Recurrent intestinal inflammation is frequently associated with aberrant bile
acid profiles and microbial community. Fucose exerts a protective effect on commensal …

Ramulus mori polysaccharide-loaded PLGA nanoparticles and their anti-inflammatory effects in vivo

Z Feng, S Peng, Z Wu, L Jiao, S Xu, Y Wu, Z Liu… - International Journal of …, 2021 - Elsevier
In this study, ramulus mori polysaccharide (RMP) was encapsulated into Poly (lactic-co-
glycolicacid)(PLGA) to form PLGA-RMP (PR). The aim of study is to investigate anti …

The communication between intestinal microbiota and ulcerative colitis: an exploration of pathogenesis, animal models, and potential therapeutic strategies

Y Hu, Z Ye, M Wu, Y She, L Li, Y Xu, K Qin, Z Hu… - Frontiers in …, 2021 - frontiersin.org
Ulcerative Colitis (UC) is a chronic inflammatory bowel disease. The prolonged course of
UC and the lack of effective treatment management make it difficult to cure, affecting the …

Gut microbiota shape the inflammatory response in mice with an epithelial defect

R Wang, M Moniruzzaman, KY Wong, P Wiid… - Gut …, 2021 - Taylor & Francis
Intestinal epithelial cell endoplasmic reticulum (ER) stress has been implicated in intestinal
inflammation. It remains unclear whether ER stress is an initiator of or a response to …

Lactobacillus paracasei L9 improves colitis by expanding butyrate-producing bacteria that inhibit the IL-6/STAT3 signaling pathway

M Deng, X Wu, X Duan, J Xu, X Yang, X Sheng… - Food & function, 2021 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a chronic intestinal inflammation that is currently
incurable. Increasing evidence indicates that supplementation with probiotics could improve …

Synergistic Protective Effect of Konjac Mannan Oligosaccharides and Bacillus subtilis on Intestinal Epithelial Barrier Dysfunction in Caco-2 Cell Model and Mice …

L Chen, S Zhang, S Wu, Z Ren, G Liu, J Wu - Frontiers in Immunology, 2021 - frontiersin.org
As the first line of defense against intestinal bacteria and toxins, intestinal epithelial cells are
always exposed to bacteria or lipopolysaccharide (LPS), whereas pathogenic bacteria or …