[HTML][HTML] Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis

V Deveaux, T Cadoudal, Y Ichigotani, F Teixeira-Clerc… - PloS one, 2009 - journals.plos.org
Background Obesity-associated inflammation is of critical importance in the development of
insulin resistance and non-alcoholic fatty liver disease. Since the cannabinoid receptor CB2 …

Evidence for the effects of yogurt on gut health and obesity

R Pei, DA Martin, DM DiMarco… - Critical reviews in food …, 2017 - Taylor & Francis
Obesity is associated with increased risk for chronic diseases, and affects both developed
and developing nations. Yogurt is a nutrient-dense food that may benefit individuals with …

Polyunsaturated fatty acids and endocannabinoids in health and disease

HR Freitas, AR Isaac, R Malcher-Lopes… - Nutritional …, 2018 - Taylor & Francis
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic
acid, DHA, and eicosapentaenoic acid, EPA) or of omega-6 (arachidonic acid, ARA) …

The expanded endocannabinoid system/endocannabinoidome as a potential target for treating diabetes mellitus

A Veilleux, V Di Marzo, C Silvestri - Current Diabetes Reports, 2019 - Springer
Abstract Purpose of Review The endocannabinoid (eCB) system, ie the receptors that
respond to the psychoactive component of cannabis, their endogenous ligands and the …

High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the …

MS Choi, YJ Kim, EY Kwon, JY Ryoo, SR Kim… - British Journal of …, 2015 - cambridge.org
The aim of the present study was to identify the genes differentially expressed in the visceral
adipose tissue in a well-characterised mouse model of high-fat diet (HFD)-induced obesity …

Mechanisms in endocrinology: endocannabinoids and metabolism: past, present and future

V Simon, D Cota - European journal of endocrinology, 2017 - academic.oup.com
The endocannabinoid system (ECS), including cannabinoid type 1 and type 2 receptors
(CB1R and CB2R), endogenous ligands called endocannabinoids and their related …

The endogenous cannabinoid system stimulates glucose uptake in human fat cells via phosphatidylinositol 3-kinase and calcium-dependent mechanisms

C Pagano, C Pilon, A Calcagno… - The Journal of …, 2007 - academic.oup.com
Background: The endogenous cannabinoid system participates in the regulation of energy
balance, and its dysregulation may be implicated in the pathogenesis of obesity. Adipose …

Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in …

L Van Gaal, X Pi-Sunyer, JP Després… - Diabetes …, 2008 - Am Diabetes Assoc
OBJECTIVE—To better define the efficacy and safety of rimonabant, the first selective
cannabinoid type 1 (CB1) receptor antagonist, in a large population of overweight and …

[HTML][HTML] Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: a key to lean phenotype

P Flachs, M Rossmeisl, O Kuda, J Kopecky - Biochimica et Biophysica Acta …, 2013 - Elsevier
We are facing a revival of the strategy to counteract obesity and associated metabolic
disorders by inducing thermogenesis mediated by mitochondrial uncoupling protein-1 …

[HTML][HTML] Endocannabinoids and the gut-brain control of food intake and obesity

NV DiPatrizio - Nutrients, 2021 - mdpi.com
Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought
to be dysregulated in obesity. We will explore new studies that suggest the …