Target Reprogramming the 3′ UTR of Tumor‐Suppressor Genes by a siRNA Composite Nanoparticle for Glioblastoma Therapy

B Gu, X Zeng, M Gong, X Li, Q Yu, Z Tan… - Advanced Functional …, 2024 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most aggressive and common adult brain tumor.
Current therapies primarily involve surgical resection, followed by chemotherapy and …

Effects of Nanomaterials on Synthesis and Degradation of the Extracellular Matrix

Z Zhou, Y Zhang, Y Zeng, D Yang, J Mo, Z Zheng… - ACS …, 2024 - ACS Publications
Extracellular matrix (ECM) remodeling is accompanied by the continuous synthesis and
degradation of the ECM components. This dynamic process plays an important role in …

Efficacy of nanoporous silica coatings on middle ear prostheses as a delivery system for antibiotics: An animal study in rabbits

R Lensing, A Bleich, A Smoczek, S Glage, N Ehlert… - Acta Biomaterialia, 2013 - Elsevier
Nanoporous silica layers are able to host molecules and release them over a certain period
of time. These local drug delivery systems for antibiotics could be a new approach in the …

Receptor‐mediated cellular uptake of nanoparticles: A switchable delivery system

L Zhang, W Fischer, E Pippel, G Hause, M Brandsch… - small, 2011 - Wiley Online Library
Lianbing Zhang,* Wiebke Fischer, Eckhard Pippel, Gerd Hause, Matthias Brandsch, and
Mato Knez* cavity.[15] In various studies, apoferritin has already served as template for the …

Amorphous silica nanoparticles promote monocyte adhesion to human endothelial cells: size‐dependent effect

D Napierska, R Quarck, LCJ Thomassen, D Lison… - Small, 2013 - Wiley Online Library
There is evidence that nanoparticles can induce endothelial dysfunction. Here, the effect of
monodisperse amorphous silica nanoparticles (SiO2‐NPs) of different diameters on …

Detoxification of hexavalent chromate by growing Paecilomyces lilacinus XLA

X Xu, L Xia, W Chen, Q Huang - Environmental Pollution, 2017 - Elsevier
In the study, the capability of Paecilomyces lilacinus XLA (CCTCC: M2012135) to reduce Cr
6+ and its main antagonistic mechanisms to Cr 6+ were experimentally evaluated. Activated …

Nanoparticles as modulators of oxidative stress

R Ganguly, AK Singh, R Kumar, A Gupta… - … in modern animal …, 2019 - Elsevier
The rapidly emerging field of nanotechnology in the recent years has led to significant
discoveries in the field of medicine and biology. Nanoparticles (NPs) with distinct …

Synthesis and characterization of novel calcium-silicate nanobioceramics with magnesium: effect of heat treatment on biological, physical and chemical properties

K Kazeli, I Tsamesidis, A Theocharidou, L Malletzidou… - Ceramics, 2021 - mdpi.com
Glass-ceramic nanopowder with a composition of 55SiO2-35CaO-10MgO (mol%) was
synthesized by the sol–gel method and was heat treated at three temperatures (T1= 835° C …

Lysosomes activating chain reactions against cancer cells with a pH-switched prodrug/procatalyst co-delivery nanosystem

J Fu, Y Zhu - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Conventional chemotherapy uses potent toxic drugs to destroy cancer cells and always
causes severe systemic toxicity in patients. In this respect, a smart and pH-switched …

Cutting-edge advancements in anticancer drug delivery and scope for theranostics using biocompatible multifunctional mesoporous silica nanoparticles

S Sarnaik, D Bhatane, SR Pamshong… - Journal of Drug Delivery …, 2024 - Elsevier
With the advancement in nanotechnology, treatment of cancer has improved significantly in
the past few decades. However, the hunt for exciting new generation of nanocarriers has no …