Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have
been predominantly used in basic and preclinical research during the last 30 years. Since …

Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …

The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Integrins are key regulators of communication between cells and with their
microenvironment. Eight members of the integrin superfamily recognize the tripeptide motif …

The recently emerged exceedingly small magnetic iron oxide nanoparticles (ES-MIONs)(< 5
nm) are promising T 1-weighted contrast agents for magnetic resonance imaging (MRI) due …

Correlative clinical evidence and experimental observations indicate that integrin adhesion
receptors, in particular those of the αV family, are relevant to cancer cell features, including …

Delivery of functional proteins into the intracellular space has been a challenging task that
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …