Increased HIV drug resistance (HIVDR) with antiretroviral therapy (ART) rollout may
jeopardize therapeutic options, especially in this era of transition to fixed-dose tenofovir …

Objectives The emergence of pretreatment drug resistance (PDR) caused by increased
usage of antiretroviral therapy (ART) represents a significant challenge to HIV management …

HIV drug resistance (HIVDR) can become a public health concern, especially in low-and
middle-income countries where genotypic testing for people initiating antiretroviral therapy …

Abstract Objectives Two Phase 3, randomized, double-blind, active-controlled studies of
initial HIV-1 treatment demonstrated that bictegravir/emtricitabine/tenofovir alafenamide …

Modern drug delivery to tackle infectious disease has drawn close to personalizing medicine
for specific patient populations. Challenges include antibiotic-resistant infections, healthcare …

Drug resistance via drug-resistant mutations in the human immunodeficiency virus (HIV)
genome is the primary cause of antiviral therapy failure. Consequently, HIV drug resistance …

The global intensification of antiretroviral therapy (ART) can lead to increased rates of HIV
drug resistance (HIVDR) mutations in treated and also in ART-naive patients. ART-naive HIV …

Objective To investigate the incidence and predictors of viraemia among individuals on
antiretroviral therapy (ART) in Harare, Zimbabwe. Methods Children (0–19 years) and adults …

Regular HIV-1 viral load monitoring is the standard of care to assess antiretroviral therapy
effectiveness in resource-rich settings. Persistently elevated viral loads indicate virologic …

There is an increasing need for innovative drug and prophylaxis discovery against malaria.
The aim of the present study was to test in vivo antiplasmodial activity of Croton …