Interaction of gut microbiome and host microRNAs with the occurrence of colorectal and breast cancer and their impact on patient immunity

S De Silva, KH Tennekoon… - OncoTargets and …, 2021 - Taylor & Francis
Breast and colorectal cancers are two primary malignancies on which most of the research
done worldwide investigates the potential genetic and environmental risk factors and …

Quantifying the genetic correlation between multiple cancer types

S Lindström, H Finucane, B Bulik-Sullivan… - … Biomarkers & Prevention, 2017 - AACR
Background: Many cancers share specific genetic risk factors, including both rare high-
penetrance mutations and common SNPs identified through genome-wide association …

In Vitro Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with In Silico Insights

H Ciftci, B Sever, N Bayrak, M Yıldız, H Yıldırım… - Pharmaceuticals, 2022 - mdpi.com
Colorectal cancer (CRC) and breast cancer are leading causes of death globally, due to
significant challenges in detection and management. The late-stage diagnosis and …

Association between breast cancer and the risk of colorectal cancer

JH Lai, G Park, LB Gerson - Gastrointestinal endoscopy, 2017 - Elsevier
Background The literature to date has suggested a potential increase in colorectal cancer
(CRC) among patients with breast cancer. Methods We performed a systematic review of the …

Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer

RR Mikaeel, JP Young, Y Li, E Smith… - Genes …, 2022 - Wiley Online Library
Colorectal cancer (CRC) incidence in young adults is rising. Identifying genetic risk factors is
fundamental for the clinical management of patients and their families. This study aimed to …

Estrogen activation by steroid sulfatase increases colorectal cancer proliferation via GPER

LC Gilligan, HP Rahman, AM Hewitt… - The Journal of …, 2017 - academic.oup.com
Context Estrogens affect the incidence and progression of colorectal cancer (CRC),
although the precise molecular mechanisms remain ill-defined. Objective The present study …

Bidirectional Mendelian randomization analysis investigating the genetic association between primary breast cancer and colorectal cancer

Y Liu, M Si, Y Qian, Y Liu, Z Wang, T Zhang… - Frontiers in …, 2024 - frontiersin.org
Purpose With the advancement in early diagnosis and treatment, the prognosis for
individuals diagnosed with breast cancer (BC) has improved significantly. The prognosis of …

Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in female patients with breast cancer or genitalia malignancies

L Xiao, T Cao, J Ou, W Liang - PeerJ, 2022 - peerj.com
Background As public awareness of health has increased and diagnostic and treatment
options have improved, the survival of patients with malignant tumors has continued to …

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal …

V Manoharan, EH Karunanayake, KH Tennekoon… - BMC cancer, 2020 - Springer
Background Breast cancer (BC) is known to be the most common malignancy in females
whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 …

Synchronous or metachronous breast and colorectal cancers in younger-than-average-age patients: a case series

J Silverstein, F Wright, D Stanfield, AJ Chien… - The …, 2024 - academic.oup.com
Background The incidence of breast and colorectal cancer (CRC) in younger-than-average-
age patients is rising and poorly understood. This is the largest study on patients with both …