[HTML][HTML] Humanized mouse models of HIV infection
PW Denton, JV García - AIDS reviews, 2011 - ncbi.nlm.nih.gov
Because of the limited tropism of HIV, in vivo modeling of this virus has been almost
exclusively limited to other lentiviruses such as SIV that reproduce many important …
exclusively limited to other lentiviruses such as SIV that reproduce many important …
[HTML][HTML] Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
New World monkeys of the genus Aotus synthesize a fusion protein (AoT5Cyp) containing
tripartite motif-containing 5 (TRIM5) and cyclophilin A (CypA) that potently blocks HIV-1 …
tripartite motif-containing 5 (TRIM5) and cyclophilin A (CypA) that potently blocks HIV-1 …
Toward a durable treatment of HIV-1 infection using RNA interference
JJM Eekels, B Berkhout - Progress in molecular biology and translational …, 2011 - Elsevier
RNA interference (RNAi) is a cellular mechanism that mediates sequence-specific gene
silencing at the posttranscriptional level. RNAi can be used as an antiviral approach against …
silencing at the posttranscriptional level. RNAi can be used as an antiviral approach against …
Expansion of Activated Memory CD4+ T Cells Affects Infectivity of CCR5-Tropic HIV-1 in Humanized NOD/SCID/JAK3null Mice
K Terahara, M Ishige, S Ikeno, Y Mitsuki, S Okada… - PloS one, 2013 - journals.plos.org
Humanized mice reconstituted with human hematopoietic cells have been developed as an
experimental animal model for human immunodeficiency virus type 1 (HIV-1) infection …
experimental animal model for human immunodeficiency virus type 1 (HIV-1) infection …
Polynucleotides encoding a human TRIM-Cyp fusion polypeptide, compositions thereof, and methods of using same
2011-12-01 Assigned to THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF
NEW YORK reassignment THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF …
NEW YORK reassignment THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF …
RNA-interference-based gene therapy approaches to HIV type-1 treatment: tackling the hurdles from bench to bedside
KJ Von Eije, B Berkhout - Antiviral Chemistry and …, 2009 - journals.sagepub.com
RNA interference (RNAi) is a cellular mechanism that can be induced by small interfering
RNAs (siRNAs) to mediate sequence-specific gene silencing by cleavage of the targeted …
RNAs (siRNAs) to mediate sequence-specific gene silencing by cleavage of the targeted …
In Vivo Modulation of Gene Expression by Lentiviral Transduction in “Human Immune System” Rag2−/−γc −/− Mice
AU van Lent, M Centlivre, M Nagasawa, JJ Karrich… - Dendritic Cell …, 2010 - Springer
Over the last two decades, several humanized mouse models have been used to
experimentally analyze the function and development of the human immune system. Recent …
experimentally analyze the function and development of the human immune system. Recent …
Production and Characterization of Humanized Rag2−/−γc−/− Mice
FM Sanchez, GI Cuadra, SJ Nielsen, A Tanner… - Mouse Models of Innate …, 2013 - Springer
Mice reconstituted with human immune cells represent a model to study the development
and functionality of the human immune system. Recent improvements in humanized mice …
and functionality of the human immune system. Recent improvements in humanized mice …
uc781: Beta-cyclodextrin complexation and formulation as an anti-hiv microbicide
H Yang - 2008 - search.proquest.com
Background. UC781, a tight-binding non-nucleotide reverse transcriptase inhibitor (NNRTI)
of HIV-1, is a thiocarboxanilide that has been identified as a potential microbicide agent …
of HIV-1, is a thiocarboxanilide that has been identified as a potential microbicide agent …
RNAi as Antiviral Therapy: The HIV-1 Case
B Berkhout, JJM Eekels - RNA Interference from Biology to Therapeutics, 2012 - Springer
RNA interference (RNAi) is a cellular mechanism that mediates sequence-specific gene
silencing. The RNAi mechanism also has therapeutic potential, and it can be used as an …
silencing. The RNAi mechanism also has therapeutic potential, and it can be used as an …