In the previous OCTO longitudinal study, we identified an immune risk phenotype (IRP) of
high CD8 and low CD4 numbers and poor proliferative response. We also demonstrated …

Sarcopenia, the age-related loss of muscle mass and strength, is a fundamental cause of
frailty, functional decline and disability. In the year 2000, $18.5 billion in health care costs …

Conclusions FXR sulfhydration is a post‐translational modification affected by hepatic
endogenous CSE/H 2 S that may promote FXR activity and attenuate NAFLD. Hepatic CSE …

Background Acromial (ASF) and scapular spine (SSF) stress fractures are well-recognized
complications of reverse shoulder arthroplasty (RSA), but much of the current data are …

Importance The Institute of Medicine set the recommended dietary allowance (RDA) for
protein at 0.8 g/kg/d for the entire adult population. It remains controversial whether protein …

Background Adverse muscle composition (MC) as measured by magnetic resonance
imaging has previously been linked to poor function, comorbidity, and increased …

Skeletal muscle is a dynamic tissue that responds adaptively to both the nature and intensity
of muscle use. This phenotypic plasticity ensures that muscle structure is linked to patterns of …

Background Malnutrition is a serious condition that develops when the human body is
deprived of or does not obtain the right amount of vital nutrients like vitamins, minerals …

Muscle protein metabolism is resistant to insulin's anabolic effect in healthy older subjects.
This is associated with reduced insulin vasodilation. We hypothesized that aerobic exercise …

The microbiome has been demonstrated to play an integral role in the maintenance of many
aspects of health that are also associated with aging. In order to identify areas of potential …