Circadian clocks as modulators of metabolic comorbidity in psychiatric disorders

R Barandas, D Landgraf, MJ McCarthy… - Current psychiatry …, 2015 - Springer
Psychiatric disorders such as schizophrenia, bipolar disorder, and major depressive
disorder are often accompanied by metabolic dysfunction symptoms, including obesity and …

[HTML][HTML] Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects

G Milos, J Antel, LK Kaufmann, N Barth, A Koller… - Translational …, 2020 - nature.com
To examine the hypothesis that normalization of low circulating leptin levels in patients with
anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity …

Appetite changes reveal depression subgroups with distinct endocrine, metabolic, and immune states

WK Simmons, K Burrows, JA Avery, KL Kerr… - Molecular …, 2020 - nature.com
There exists little human neuroscience research to explain why some individuals lose their
appetite when they become depressed, while others eat more. Answering this question may …

Clinical features and management of non-HIV–related lipodystrophy in children: a systematic review

N Gupta, N Asi, W Farah, J Almasri… - The Journal of …, 2017 - academic.oup.com
Context: Lipodystrophy syndromes are characterized by generalized or partial absence of
adipose tissue. Objective: We conducted a systematic review to synthesize data on clinical …

[HTML][HTML] Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color …

G Audira, S Sarasamma, JR Chen, S Juniardi… - International journal of …, 2018 - mdpi.com
Leptin, a hormone secreted by peripheral adipose tissues, regulates the appetite in animals.
Recently, evidence has shown that leptin also plays roles in behavioral response in addition …

[HTML][HTML] Behavioral abnormalities in knockout and humanized tau mice

RA Gonçalves, N Wijesekara, PE Fraser… - Frontiers in …, 2020 - frontiersin.org
Microtubule-associated protein tau assists in stabilizing microtubules and has been
particularly implicated in Alzheimer's disease (AD). Given the importance of tau to AD …

[HTML][HTML] Cluster analysis in gambling disorder based on sociodemographic, neuropsychological, and neuroendocrine features regulating energy homeostasis

I Baenas, B Mora-Maltas, M Etxandi, I Lucas… - Comprehensive …, 2024 - Elsevier
Background The heterogeneity of gambling disorder (GD) has led to the identification of
different subtypes, mostly including phenotypic features, with distinctive implications on the …

Leptin/LepRb in the ventral tegmental area mediates anxiety-related behaviors

J Liu, M Guo, XY Lu - International journal of …, 2016 - academic.oup.com
Background: Leptin, an adipose-derived hormone, has been implicated in emotional
regulation. We have previously shown that systemic administration of leptin produces …

Explicating the role of amygdala substructure alterations in the link between hypoleptinemia and rumination in anorexia nervosa

ML Wronski, C Hohnemann… - Acta Psychiatrica …, 2023 - Wiley Online Library
Objective The amygdaloid complex plays a pivotal role in emotion processing and has been
associated with rumination transdiagnostically. In anorexia nervosa (AN), we previously …

[HTML][HTML] Polyphenol-rich beverage consumption affecting parameters of the lipid metabolism in healthy subjects

C Rahn, T Bakuradze, S Stegmüller, J Galan… - International journal of …, 2023 - mdpi.com
Polyphenols are a diverse and widely distributed class of secondary metabolites, which
possess numerous beneficial properties including a modulation of glucose and lipid …