Metallodrugs in cancer nanomedicine
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
Stimuli-responsive therapeutic metallodrugs
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …
metal-based drugs for several decades, whereas problems such as drug-resistance and …
Classification of metal-based drugs according to their mechanisms of action
Metal-based drugs and imaging agents are extensively used in the clinic for the treatment
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …
Radioactive transition metals for imaging and therapy
E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …
emission tomography (PET) and single-photon imaging, including single-photon emission …
Matching chelators to radiometals for radiopharmaceuticals
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …
properly harnessed, these have valuable emission properties that can be used for …
Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …
variable oxidation states, diverse range of geometries and coordination numbers …
Mechanism unravelling for ultrafast and selective 99 TcO 4− uptake by a radiation-resistant cationic covalent organic framework: a combined radiological experiment …
L He, S Liu, L Chen, X Dai, J Li, M Zhang, F Ma… - Chemical …, 2019 - pubs.rsc.org
99Tc is one of the most problematic fission products in the nuclear fuel cycle owing to its
large inventory in used nuclear fuel, long half-life, potential radiation hazard, high …
large inventory in used nuclear fuel, long half-life, potential radiation hazard, high …
[HTML][HTML] Prospective of 68Ga-radiopharmaceutical development
I Velikyan - Theranostics, 2014 - ncbi.nlm.nih.gov
Abstract Positron Emission Tomography (PET) experienced accelerated development and
has become an established method for medical research and clinical routine diagnostics on …
has become an established method for medical research and clinical routine diagnostics on …
Clinical applications of Gallium-68
SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …
A picture of modern Tc-99m radiopharmaceuticals: Production, chemistry, and applications in molecular imaging
A Boschi, L Uccelli, P Martini - Applied Sciences, 2019 - mdpi.com
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-
imaging applications. Its peculiar physical and chemical properties make it particularly …
imaging applications. Its peculiar physical and chemical properties make it particularly …