Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review

AT Roux, L Maharaj, O Oyegoke, OP Akoniyon… - Frontiers in …, 2021 - frontiersin.org
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …

Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon: a systematic review and meta-analysis (1998–2020)

PTN Niba, AM Nji, MS Evehe, IM Ali, PM Netongo… - Malaria Journal, 2021 - Springer
Background Malaria remains highly endemic in Cameroon. The rapid emergence and
spread of drug resistance was responsible for the change from monotherapies to artemisinin …

Multiple single-nucleotide polymorphism detection for antimalarial pyrimethamine resistance via allele-specific PCR coupled with gold nanoparticle-based lateral flow …

T Jiang, Y Huang, W Cheng, Y Sun, W Wei… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Molecular genotyping holds tremendous potential to detect antimalarial drug resistance
(ADR) related to single nucleotide polymorphisms (SNPs). However, it relies on the use of …

Analysis of sulphadoxine–pyrimethamine resistance-associated mutations in Plasmodium falciparum isolates obtained from asymptomatic pregnant women in Ogun …

KA Fagbemi, SA Adebusuyi, D Nderu… - Infection, Genetics and …, 2020 - Elsevier
Intermittent preventive treatment in pregnancy with sulphadoxine− pyrimethamine (IPTp-SP)
is one of the main strategies for protecting pregnant women, fetus, and their new-born …

The prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine among pregnant women at first antenatal clinic attendance and delivery in the forest …

DK Dosoo, JA Bailey, KP Asante, FB Oppong, K Niaré… - Plos one, 2022 - journals.plos.org
Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-
SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …

A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates …

AJ Adegbola, OA Ijarotimi, AE Ubom, BA Adesoji… - Malaria Journal, 2023 - Springer
Background Malaria is a major public health issue with substantial risks among vulnerable
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …

Historical trends and new surveillance of Plasmodium falciparum drug resistance markers in Angola

ER Ebel, F Reis, DA Petrov, S Beleza - Malaria Journal, 2021 - Springer
Background Plasmodium falciparum resistance to chloroquine (CQ) and sulfadoxine-
pyrimethamine (SP) has historically posed a major threat to malaria control throughout the …

Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Central Africa between 2016 and 2021: wide geographic …

X Wang, X Zhang, H Chen, Q Lu, W Ruan… - Microbiology …, 2022 - Am Soc Microbiol
Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs.
Monitoring molecular markers in exported malaria infections provides an efficient way to …

First Detection in West Africa of a Mutation That May Contribute to Artemisinin Resistance Plasmodium falciparum

H Zhao, L Pi, L Zhao, Y Qin, W Zeng, Z Xiang… - Frontiers in …, 2021 - frontiersin.org
Background: The spread of drug resistance has seriously impacted the effective treatment of
infection with the malaria parasite, Plasmodium falciparum. Continuous monitoring of …

[HTML][HTML] High Frequency Mutations in pfdhfr and pfdhps of Plasmodium falciparum in Response to Sulfadoxine-Pyrimethamine: A Cross-Sectional Survey in …

H Yan, J Feng, J Yin, F Huang, X Kong, K Lin… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Sulfadoxine-pyrimethamine (SP) is recommended for intermittent preventive
treatment in Africa against Plasmodium falciparum infection. However, increasing SP …