Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease
W MacNee - Proceedings of the American Thoracic Society, 2005 - atsjournals.org
An imbalance between oxidants and antioxidants is considered to play a role in the
pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable …
pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable …
Scientific rationale for inhaled combination therapy with long-acting β2-agonists and corticosteroids
PJ Barnes - European Respiratory Journal, 2002 - Eur Respiratory Soc
The addition of an inhaled long-acting β2-agonist (LABA) to an inhaled corticosteroid (ICS)
gives optimal control of asthma in most patients and two fixed combination inhalers …
gives optimal control of asthma in most patients and two fixed combination inhalers …
ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets
C Bizzarri, AR Beccari, R Bertini, MR Cavicchia… - Pharmacology & …, 2006 - Elsevier
ELR+ CXC chemokines, by direct interaction with their cell surface receptors CXC
chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to …
chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to …
Prospects for new drugs for chronic obstructive pulmonary disease
PJ Barnes, TT Hansel - The Lancet, 2004 - thelancet.com
No currently available treatments have been shown to slow the progression of chronic
obstructive pulmonary disease (COPD) or suppress the inflammation in small airways and …
obstructive pulmonary disease (COPD) or suppress the inflammation in small airways and …
Delivery technologies for orally inhaled products: an update
Orally inhaled products have well-known benefits. They allow for effective local
administration of many drugs for the treatment of pulmonary disease, and they allow for …
administration of many drugs for the treatment of pulmonary disease, and they allow for …
New treatments for COPD
PJ Barnes - Nature reviews Drug discovery, 2002 - nature.com
COPD is one of the most common diseases in the world, and there is a global increase in
prevalence, but there are no drugs available at present that halt the relentless progression of …
prevalence, but there are no drugs available at present that halt the relentless progression of …
[图书][B] An atlas of chronic obstructive pulmonary disease
TT Hansel, PJ Barnes - 2003 - taylorfrancis.com
Despite being the most common respiratory disorder in the developed world and the fourth
leading cause of death in the US, chronic obstructive pulmonary disease (COPD) has …
leading cause of death in the US, chronic obstructive pulmonary disease (COPD) has …
Developments in allergen‐specific immunotherapy: from allergen extracts to allergy vaccines bypassing allergen‐specific immunoglobulin E and T cell reactivity
M Focke, I Swoboda, K Marth… - Clinical & Experimental …, 2010 - Wiley Online Library
Allergen‐specific immunotherapy (SIT) is the only specific and disease‐modifying approach
for the treatment of allergy but several disadvantages have limited its broad applicability. We …
for the treatment of allergy but several disadvantages have limited its broad applicability. We …
Chronic obstructive pulmonary disease• 12: New treatments for COPD
PJ Barnes - Thorax, 2003 - thorax.bmj.com
Drugs currently available or under development for the treatment of chronic obstructive
pulmonary disease (COPD) are reviewed. More research on the basic cellular and …
pulmonary disease (COPD) are reviewed. More research on the basic cellular and …
Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD.
TT Hansel, PJ Barnes - Drugs of today (Barcelona, Spain: 1998), 2002 - europepmc.org
Tiotropium bromide (Spiriva, BA679BR, Boehringer Ingelheim) is a novel inhaled, long-
acting anticholinergic bronchodilator that is employed as a once-daily maintenance …
acting anticholinergic bronchodilator that is employed as a once-daily maintenance …