[HTML][HTML] Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

[HTML][HTML] The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives

S Wang, Y Zheng, F Yang, L Zhu, XQ Zhu… - Signal transduction and …, 2021 - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

[HTML][HTML] Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer

Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

[HTML][HTML] Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

[HTML][HTML] Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

Microfluidic strategies for the isolation and profiling of exosomes

J Bai, X Wei, X Zhang, C Wu, Z Wang, M Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes are nanoscale extracellular vesicles carrying various cargos, which play a
significant rule in intercellular communication, disease diagnosis and treatment …

[HTML][HTML] Revolutionizing anti-tumor therapy: unleashing the potential of B cell-derived exosomes

J Xiong, H Chi, G Yang, S Zhao, J Zhang… - Frontiers in …, 2023 - frontiersin.org
B cells occupy a vital role in the functioning of the immune system, working in tandem with T
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …

Extracellular‐vesicle‐based drug delivery systems for enhanced antitumor therapies through modulating the cancer‐immunity cycle

T Yong, Z Wei, L Gan, X Yang - Advanced Materials, 2022 - Wiley Online Library
Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …