Nicotine underlies tobacco addiction, influences tobacco use patterns, and is used as a
pharmacological aid to smoking cessation. The absorption, distribution and disposition …

Nicotine is of importance as the addictive chemical in tobacco, pharmacotherapy for
smoking cessation, a potential medication for several diseases, and a useful probe drug for …

Nicotine is a naturally occurring alkaloid found in many plants. The principal sources of
nicotine exposure is through the use of tobacco, nicotine containing gum and nicotine …

The cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several clinically relevant
substrates, including nicotine—the primary psychoactive component in cigarette smoke. The …

Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

OBJECTIVES This study was designed to compare the effects of inhaled carbon monoxide
(CO), administered to achieve concentrations similar to those found in cigarette smoking …

The rate of nicotine metabolism is hypothesized to be a determinant of how much a person
smokes. That is, rapid metabolizers would be expected to need more nicotine and, therefore …

Background: Lung cancer rates are lower in Asians and Latinos than in whites. Ethnic
differences in nicotine metabolism might explain, in part, ethnic differences in cigarette …

Menthol is the only tobacco additive promoted and advertised by the tobacco industry.
Although a considerable body of research has examined the effects of menthol when it is …

The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes,
transporting gametes in opposite directions to the site of fertilization, providing a suitable …