The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
Health benefits of quercetin in age-related diseases
Polyphenols are the known group of phytochemicals that essentially consists of phenolic
rings. These are the plant product present in varied fruits and vegetables. These secondary …
rings. These are the plant product present in varied fruits and vegetables. These secondary …
Wound healing: cellular mechanisms and pathological outcomes
HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …
Quercetin: its main pharmacological activity and potential application in clinical medicine
D Yang, T Wang, M Long, P Li - Oxidative Medicine and …, 2020 - Wiley Online Library
Quercetin is a flavonoid compound widely present in plants and exhibits a variety of
biological activities. Research on quercetin has shown its potential for medical application …
biological activities. Research on quercetin has shown its potential for medical application …
Quercetin and metabolic syndrome: A review
Metabolic syndrome (MetS) is a complex of diseases that lead to mortality due to the
development of cardiovascular problems. Quercetin, as an important flavonoid, has various …
development of cardiovascular problems. Quercetin, as an important flavonoid, has various …
Therapeutic potential of quercetin: new insights and perspectives for human health
Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …
Polyphenols: A concise overview on the chemistry, occurrence, and human health
This review gives an updated picture of each class of phenolic compounds and their
properties. The most common classification implies the subdivision of phenolics in two main …
properties. The most common classification implies the subdivision of phenolics in two main …
Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential
The increase in life expectancy has boosted the incidence of age-related pathologies
beyond social and economic sustainability. Consequently, there is an urgent need for …
beyond social and economic sustainability. Consequently, there is an urgent need for …
Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus
J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …
Anti-obesity effects of polyphenol intake: Current status and future possibilities
M Boccellino, S D'Angelo - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of obesity has steadily increased worldwide over the past three decades.
The conventional approaches to prevent or treat this syndrome and its associated …
The conventional approaches to prevent or treat this syndrome and its associated …