[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

MG Cox, TP Peacock, WT Harvey, J Hughes… - Nature Reviews …, 2023 - nature.com
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
and are especially important in high-risk individuals where vaccination is not an option …

The emergence and epidemic characteristics of the highly mutated SARS‐CoV‐2 Omicron variant

D Tian, Y Sun, H Xu, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
Recently, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
variant (B. 1.1. 529) was first identified in Botswana in November 2021. It was first reported …

[HTML][HTML] Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2

P Han, L Li, S Liu, Q Wang, D Zhang, Z Xu, P Han, X Li… - Cell, 2022 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic continues worldwide with
many variants arising, some of which are variants of concern (VOCs). A recent VOC, omicron …

COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

The puzzling mutational landscape of the SARS‐2‐variant Omicron

J Fantini, N Yahi, P Colson, H Chahinian… - Journal of medical …, 2022 - Wiley Online Library
The recently emerging SARS‐CoV‐2 variant omicron displays an unusual association of 30
mutations, 3 deletions, and 1 insertion. To analyze the impact of this atypic mutational …

Twin combination of Omicron and Delta variants triggering a tsunami wave of ever high surges in COVID‐19 cases: a challenging global threat with a special focus on …

RK Mohapatra, R Tiwari, AK Sarangi… - Journal of medical …, 2022 - Wiley Online Library
The emergence of Omicron (B. 1.1. 529) variant of SARS‐CoV‐2 has resulted into a very
massive surge in COVID‐19 cases worldwide. Due to continuous emergence of multiple …

Mutations in SARS-CoV-2 structural proteins: a global analysis

M Abavisani, K Rahimian, B Mahdavi, S Tokhanbigli… - Virology Journal, 2022 - Springer
Background Emergence of new variants mainly variants of concerns (VOC) is caused by
mutations in main structural proteins of severe acute respiratory syndrome coronavirus 2 …

mRNA vaccines against SARS‐CoV‐2 variants delivered by lipid nanoparticles based on novel ionizable lipids

K Chen, N Fan, H Huang, X Jiang, S Qin… - Advanced functional …, 2022 - Wiley Online Library
SARS‐CoV‐2 variants are now still challenging all the approved vaccines, including mRNA
vaccines. There is an urgent need to develop new generation mRNA vaccines with more …

[HTML][HTML] Omicron variant: Current insights and future directions

R Rana, R Kant, RS Huirem, D Bohra… - Microbiological …, 2022 - Elsevier
The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2
Omicron variant (B. 1.1. 529) after appearing to be persistently spreading for the more than …

[HTML][HTML] Challenges of SARS-CoV-2 Omicron Variant and appropriate countermeasures

W Shao, W Zhang, X Fang, D Yu, X Wang - Journal of Microbiology …, 2022 - Elsevier
Abstract The Omicron (B. 1.1. 529) variant was first reported in South Africa and rapidly
spread worldwide in early November 2021. This caused panic in various countries, so it is …