Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …

Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Circulating platelets interact with leukocytes to modulate host immune and thrombotic
responses. In sepsis, platelet-leukocyte interactions are increased and have been …

In addition to their hemostatic function, platelets play an important role in regulating the
inflammatory response. The platelet NLRP3 inflammasome not only promotes interleukin-1β …

This review evaluates the role of platelets in bleeding risk among patients with
hematological disease and thrombocytopenia. Platelets are pivotal in primary hemostasis …

There is no therapeutic intervention proven to prevent acute respiratory distress syndrome
(ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore …

Background Inflammation plays a crucial role in cancer development. In this study, we
evaluate the prognostic values of systemic inflammation markers such as neutrophil-to …

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …

Platelets have classically been well recognized for their crucial role in hemostasis; however,
it is increasingly evident that platelets are more versatile than originally thought because …

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder in which, via
unresolved mechanisms, platelets and megakaryocytes (MKs) are targeted by …