Vaccinology: time to change the paradigm?

CS Benn, AB Fisker, A Rieckmann, S Sørup… - The lancet infectious …, 2020 - thelancet.com
The existing vaccine paradigm assumes that vaccines only protect against the target
infection, that effective vaccines reduce mortality corresponding to the target infection's …

Do vaccines increase or decrease susceptibility to diseases other than those they protect against?

A Rubio-Casillas, CM Rodriguez-Quintero… - Vaccine, 2023 - Elsevier
Contrary to the long-held belief that the effects of vaccines are specific for the disease they
were created; compelling evidence has demonstrated that vaccines can exert positive or …

[HTML][HTML] National immunization campaigns with oral polio vaccine reduce all-cause mortality: a natural experiment within seven randomized trials

A Andersen, AB Fisker, A Rodrigues… - Frontiers in public …, 2018 - frontiersin.org
Background A recent WHO review concluded that live BCG and measles vaccine (MV) may
have beneficial non-specific effects (NSEs) reducing mortality from non-targeted diseases …

A biological approach to adult sex differences in skeletal indicators of childhood stress

L O'Donnell, EC Hill, AS Anderson… - American Journal of …, 2022 - Wiley Online Library
Objectives In previous work examining the etiology of cribra orbitalia (CO) and porotic
hyperostosis (PH) in a contemporary juvenile mortality sample, we noted that males had …

A two-center randomized trial of an additional early dose of measles vaccine: effects on mortality and measles antibody levels

AB Fisker, E Nebie, A Schoeps… - Clinical Infectious …, 2018 - academic.oup.com
Background In addition to protecting against measles, measles vaccine (MV) may have
beneficial nonspecific effects. We tested the effect of an additional early MV on mortality and …

[HTML][HTML] Revised World Health Organization (WHO)'s causality assessment of adverse events following immunization—a critique

J Puliyel, P Naik - F1000Research, 2018 - ncbi.nlm.nih.gov
Abstract The World Health Organisation (WHO) has recently revised how adverse events
after immunization (AEFI) are classified. Only reactions that have previously been …

WHO's malaria vaccine study represents a “serious breach of international ethical standards”

P Doshi - bmj, 2020 - bmj.com
WHO’s malaria vaccine study represents a “serious breach of international ethical standards” |
The BMJ Skip to main content Intended for healthcare professionals Access provided by Google …

[HTML][HTML] Evidence of increase in mortality after the introduction of diphtheria–tetanus–pertussis vaccine to children aged 6–35 months in Guinea-Bissau: a time for …

P Aaby, SW Mogensen, A Rodrigues… - Frontiers in public …, 2018 - frontiersin.org
Background Whole-cell diphtheria–tetanus–pertussis (DTP) and oral polio vaccine (OPV)
were introduced to children in Guinea-Bissau in 1981. We previously reported that DTP in …

WHO's rollout of malaria vaccine in Africa: can safety questions be answered after only 24 months?

P Aaby, AB Fisker, A Björkman, CS Benn - BMJ, 2020 - bmj.com
WHO’s rollout of malaria vaccine in Africa: can safety questions be answered after only 24
months? Page 1 WHO’s rollout of malaria vaccine in Africa: can safety questions be …

[HTML][HTML] Neonatal and child mortality data in retrospective population-based surveys compared with prospective demographic surveillance: EN-INDEPTH study

T Nareeba, F Dzabeng, N Alam, GA Biks… - Population health …, 2021 - Springer
Background Global mortality estimates remain heavily dependent on household surveys in
low-and middle-income countries, where most under-five deaths occur. Few studies have …