Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

The main limitation to the success of central nervous system (CNS) therapies lies in the
difficulty for drugs to cross the blood–brain barrier (BBB) and reach the brain. Regarding its …

Nose-to-brain drug delivery has been of great interest for the treatment of many central
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …

The discovery of effective drugs for the treatment of neurodegenerative disorders (NDs) is a
deadlock. Due to their complex etiology and high heterogeneity, progresses in the …

In the design of vaccine generation, significant attempts have been made to produce novel
vaccines and, as well, to increase the effectiveness of available vaccines versus particular …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …

Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …

Nasal drug delivery has been employed as an alternate and convenient route for the
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …

Phenolic compounds are a large, heterogeneous group of secondary metabolites found in
various plants and herbal substances. From the perspective of dermatology, the most …