Metabolic dysfunction in the regulation of the NLRP3 inflammasome activation: A potential target for diabetic nephropathy

W Zhao, L Zhou, P Novák, X Shi, CB Lin… - Journal of Diabetes …, 2022 - Wiley Online Library
Metabolic dysfunction plays a key role in the development of diabetic nephropathy (DN).
However, the exact effects and mechanisms are still unclear. The pyrin domain‐containing …

Gut microbiota-mediated IL-22 alleviates metabolic inflammation

K Wang, M Zhou, H Si, J Ma - Life Sciences, 2023 - Elsevier
Low-grade chronic inflammation, also known as metabolic inflammation, promotes the
development of metabolic diseases. Increasing evidence suggests that changes in gut …

IL-22: a potential mediator of associations between urinary polycyclic aromatic hydrocarbon metabolites with fasting plasma glucose and type 2 diabetes

M Cheng, Y Zhou, B Wang, G Mu, J Ma, M Zhou… - Journal of Hazardous …, 2021 - Elsevier
Previous studies found that exposure to polycyclic aromatic hydrocarbons (PAHs) was
associated with type 2 diabetes (T2D) prevalence. However, the potential mechanism is still …

Atorvastatin and losartan may upregulate renalase activity in hypertension but not coronary artery diseases: the role of gene polymorphism

H Akbari, G Asadikaram, S Vakili… - Journal of cellular …, 2019 - Wiley Online Library
The aim is to explore the treatment effect of coronary artery disease (CAD) and hypertension
on plasma levels of renalase activity and also the possible association of renalase …

Association of Klotho gene polymorphism with hypertension and coronary artery disease in an Iranian population

H Akbari, G Asadikaram, H Aria, S Fooladi… - BMC cardiovascular …, 2018 - Springer
Background Klotho, possibly an age-regulating protein, is considered an important factor
contributing to the lifespan and pathophysiology of hypertension and coronary artery …

Atorvastatin, losartan and captopril may upregulate IL-22 in hypertension and coronary artery disease; the role of gene polymorphism

H Akbari, G Asadikaram, A Jafari, M Nazari-Robati… - Life sciences, 2018 - Elsevier
Abstract Aims Interleukin-22 (IL-22) may be considered as an important cytokine in
maintenance and progression of hypertension and coronary artery disease (CAD). The aim …

CD36 gene polymorphism rs1761667 (G> A) is associated with hypertension and coronary artery disease in an Iranian population

MA Momeni-Moghaddam, G Asadikaram… - BMC cardiovascular …, 2019 - Springer
Background CD36 is associated with regulation of lipid metabolism, atherosclerosis, and
blood pressure. Moreover, its variation may be involved in the development of hypertension …

[HTML][HTML] Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders

J Gu, P Zhou, Y Liu, Q Xu, X Chen, M Chen… - Molecular and Cellular …, 2022 - Elsevier
The prevalence of metabolic diseases has become a severe public health problem.
Previously, we reported that Interleukin-22 (IL-22) was independently associated with type 2 …

The effects of glucagon-like peptide-1 receptor agonists on glycemic control and anthropometric profiles among diabetic patients with non-alcoholic fatty liver disease …

P Nowrouzi-Sohrabi, S Rezaei, M Jalali… - European Journal of …, 2021 - Elsevier
This study was undertaken to assess the effects of glucagon-like peptide-1 receptor agonists
(GLP-1RAs), mainly liraglutide and exenatide, on glycemic control and anthropometric …

Association between cognitive impairment and blood pressure among patients with type ii diabetes mellitus in Southern Iran

S Jamalnia, S Javanmardifard, H Akbari… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose Both type 2 diabetes mellitus (T2DM) and hypertension are regarded as life-
threatening diseases known to be risk factors for vascular diseases. They may be associated …