A journey into the world of insect lipid metabolism

U Toprak, D Hegedus, C Doğan… - Archives of insect …, 2020 - Wiley Online Library
Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Lipid metabolism in insect disease vectors

KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-
transmitted disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease …

Insulin receptor deficiency reduces lipid synthesis and reproductive function in the insect Rhodnius prolixus

G Silva-Oliveira, IF De Paula, JM Medina… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Rhodnius prolixus, a vector of Chagas disease, is a hematophagous insect that feeds
exclusively on blood. Each blood meal is digested within the first fourteen days after feeding …

What happens after a blood meal? A transcriptome analysis of the main tissues involved in egg production in Rhodnius prolixus, an insect vector of Chagas disease

J Leyria, I Orchard, AB Lange - PLoS neglected tropical diseases, 2020 - journals.plos.org
The blood-sucking hemipteran Rhodnius prolixus is a vector of Chagas disease, one of the
most neglected tropical diseases affecting several million people, mostly in Latin America …

Genes, transcription factors and enzymes involved in lipid metabolism in fin fish

CL Ayisi, C Yamei, JL Zhao - Agri Gene, 2018 - Elsevier
Lipid metabolism in fish which is a complex phenomenon has been studied in the past few
years as its gradually gaining interest from researchers. Lipids serve essential roles in both …

Alterations in energy metabolism of Rhodnius prolixus induced by Trypanosoma rangeli infection

LC Andrade, D Majerowicz, PL Oliveira… - Insect Biochemistry and …, 2023 - Elsevier
Trypanosoma rangeli is a protozoan parasite that infects triatomines and mammals in the
Americas, producing mixed infections with Trypanosoma cruzi, the etiological agent of …

Deficiency of Acetyl-CoA Carboxylase Impairs Digestion, Lipid Synthesis, and Reproduction in the Kissing Bug Rhodnius prolixus

B Moraes, V Braz, S Santos-Araujo, IA Oliveira… - Frontiers in …, 2022 - frontiersin.org
Rhodnius prolixus is a hematophagous insect, vector of Chagas disease. After feeding, as
blood is slowly digested, amino acids are used as substrates to fuel lipid synthesis, and …

GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway

G Fan, Y Li, Y Zong, X Suo, Y Jia, M Gao… - Cell Death & Disease, 2023 - nature.com
In the process of inflammatory activation, macrophages exhibit lipid metabolism disorders
and accumulate lipid droplets. Kupffer cells (KCs) are the resident hepatic macrophage with …

Knockdown of carnitine palmitoyltransferase I (CPT1) reduces fat body lipid mobilization and resistance to starvation in the insect vector Rhodnius prolixus

IF De Paula, S Santos-Araujo, D Majerowicz… - Frontiers in …, 2023 - frontiersin.org
The energy stored in fatty acids is essential for several critical activities of insects, such as
embryogenesis, oviposition, and flight. Rhodnius prolixus is an obligatory hematophagous …

Silencing of ATG6 and ATG8 promotes increased levels of triacylglycerol (TAG) in the fat body during prolonged starvation periods in the Chagas disease vector …

S Santos-Araujo, L Bomfim, LO Araripe, R Bruno… - Insect Biochemistry and …, 2020 - Elsevier
Rhodnius prolixus is an obligatorily hematophagous insect known as an important vector of
Chagas disease. Autophagy is a conserved cellular mechanism that acts in response to …