The potential of the mevalonate pathway for enhanced isoprenoid production

P Liao, A Hemmerlin, TJ Bach, ML Chye - Biotechnology advances, 2016 - Elsevier
The cytosol-localised mevalonic acid (MVA) pathway delivers the basic isoprene unit
isopentenyl diphosphate (IPP). In higher plants, this central metabolic intermediate is also …

A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?

A Hemmerlin, JL Harwood, TJ Bach - Progress in lipid research, 2012 - Elsevier
When compared to other organisms, plants are atypical with respect to isoprenoid
biosynthesis: they utilize two distinct and separately compartmentalized pathways to build …

Biosynthesis of plant‐derived flavor compounds

W Schwab, R Davidovich‐Rikanati… - The plant …, 2008 - Wiley Online Library
Plants have the capacity to synthesize, accumulate and emit volatiles that may act as aroma
and flavor molecules due to interactions with human receptors. These low‐molecular‐weight …

[HTML][HTML] Triterpenoid biosynthesis and engineering in plants

S Sawai, K Saito - Frontiers in plant science, 2011 - frontiersin.org
Triterpenoid saponins are a diverse group of natural products in plants and are considered
defensive compounds against pathogenic microbes and herbivores. Because of their …

Lavandula Essential Oils: A Current Review of Applications in Medicinal, Food, and Cosmetic Industries of Lavender

R Wells, F Truong, AM Adal… - Natural Product …, 2018 - journals.sagepub.com
The global essential oil market has been steadily increasing in size over the past few years,
and is estimated to reach ca. $7.5 billion USD per annum by 2018. Lavenders (Lavandula; …

Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures

G Kai, H Xu, C Zhou, P Liao, J Xiao, X Luo, L You… - Metabolic …, 2011 - Elsevier
Tanshinone is a group of active diterpenes widely used in treatment of cardiovascular
diseases. Here, we report the introduction of genes encoding 3-hydroxy-3-methylglutaryl …

Contribution of isopentenyl phosphate to plant terpenoid metabolism

LK Henry, ST Thomas, JR Widhalm, JH Lynch… - Nature plants, 2018 - nature.com
Plant genomes encode isopentenyl phosphate kinases (IPKs) that reactivate isopentenyl
phosphate (IP) via ATP-dependent phosphorylation, forming the primary metabolite …

Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities

BM Lange, A Ahkami - Plant biotechnology journal, 2013 - Wiley Online Library
Terpenoids (aka isoprenoids) represent the most diverse class of natural products found in
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …

[HTML][HTML] Towards efficient terpenoid biosynthesis: manipulating IPP and DMAPP supply

Q Wang, S Quan, H Xiao - Bioresources and Bioprocessing, 2019 - Springer
Terpenoids are a group of largest natural products with important biological functions, and
their efficient biosynthesis is of particular importance to both academia and industry. As the …

In vitro culture of lavenders (Lavandula spp.) and the production of secondary metabolites

S Gonçalves, A Romano - Biotechnology advances, 2013 - Elsevier
Lavenders (Lavandula spp., Lamiaceae) are aromatic ornamental plants that are used
widely in the food, perfume and pharmaceutical industries. The large-scale production of …