Autoantibodies in autoimmune liver disease—clinical and diagnostic relevance

M Sebode, C Weiler-Normann, T Liwinski… - Frontiers in …, 2018 - frontiersin.org
Testing for liver-related autoantibodies should be included in the workup of patients with
hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not …

Autoimmune hepatitis: progress from global immunosuppression to personalised regulatory T cell therapy

NN Than, HC Jeffery, YH Oo - Canadian Journal of …, 2016 - Wiley Online Library
Autoimmune hepatitis (AIH) is an immune mediated liver injury. The precise aetiology of AIH
is still unknown but current evidence suggests both genetic and environmental factors are …

[HTML][HTML] BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus

HC Chuang, MH Chen, YM Chen, HY Yang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Serum-derived exosomes are correlated with disease severity of human
systemic lupus erythematosus (SLE). The proteins in the T-cell-derived exosomes from SLE …

Association of extrahepatic manifestations with autoimmune hepatitis

GW Wong, MA Heneghan - Digestive diseases, 2015 - karger.com
For many patients with autoimmune hepatitis (AIH), the presence of extrahepatic features is
well recognised both at the time of presentation and during long-term follow-up …

Autoimmune serology testing in clinical practice: an updated roadmap for the diagnosis of autoimmune hepatitis

GN Dalekos, NK Gatselis - European Journal of Internal Medicine, 2023 - Elsevier
Diagnosis of autoimmune hepatitis (AIH) is in most cases challenging for clinicians as there
is not a single specific laboratory or histological marker to diagnose or exclude the presence …

Regulatory T-cell deficiency leads to features of autoimmune liver disease overlap syndrome in scurfy mice

K Yilmaz, S Haeberle, YO Kim, MJ Fritzler… - Frontiers in …, 2023 - frontiersin.org
Introduction Scurfy mice have a complete deficiency of functional regulatory T cells (Treg)
due to a frameshift mutation in the Foxp3 gene. The impaired immune homeostasis results in …

S2k Leitlinie Autoimmune Lebererkrankungen

DM Crohn, C ulcerosa Vereinigung… - Zeitschrift für …, 2017 - thieme-connect.com
Diese Leitlinie wurde unter Federführung der DGVS und mit Beteiligung benachbarter
Fachgebiete erstellt und soll als praktische Hilfe für die Diagnostik und Therapie der …

Investigating the causal relationship and potential shared diagnostic genes between primary biliary cholangitis and systemic lupus erythematosus using bidirectional …

T Tao, A Tang, L Lv, J Yuan, L Wu, L Zhao… - Frontiers in …, 2024 - frontiersin.org
Background The co-occurrence of primary biliary cholangitis (PBC) and systemic lupus
erythematosus (SLE) has been consistently reported in observational studies. Nevertheless …

Autoantibodies associated with primary biliary cholangitis are common among patients with systemic lupus erythematosus even in the absence of elevated liver …

A Ahmad, R Heijke, P Eriksson… - Clinical & …, 2021 - academic.oup.com
Knowledge of concomitant autoimmune liver diseases (AILD) is more detailed in primary
Sjögren's syndrome (pSS) compared to systemic lupus erythematosus (SLE). Herein, the …

The use of biologics in the treatment of autoimmune liver disease

C Chang, A Tanaka, C Bowlus… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Autoimmune liver diseases include autoimmune hepatitis (AIH), primary biliary
cholangitis (PBC), primary sclerosing cholangitis (PSC) and juvenile autoimmune hepatitis …