Objective Laryngopharyngeal reflux (LPR) is a common illness of otolaryngology visits. Over
the past few years, pepsin has become a promising marker of LPR. The objective of the …

Objective Current diagnostic methods for gastro-oesophageal reflux disease (GORD) have
moderate sensitivity/specificity and can be invasive and expensive. Pepsin detection in …

Recurrent respiratory problems are common in children with severe neurodisability, and
respiratory deterioration is a leading cause of premature death in this group. Although the …

Objectives Laryngopharyngeal reflux (LPR) and biliary duodenogastric reflux can cause
damage to the laryngeal mucosa and voice disorders. The aim of this study was to find out …

Objectives/Hypothesis To determine salivary pepsin levels as a function of collection time.
Study Design A prospective, case‐control study. Methods We selected 57 patients with …

Background Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting
considerable attention. In recent years, the causal role between LPR and laryngeal …

Background Laryngopharyngeal reflux (LPR) can induce laryngeal hyper-responsiveness, a
unifying feature underlying chronic cough and vocal cord dysfunction. The diagnosis of LPR …

Objectives We aimed to confirm the presence of pepsinA in the nasal secretions and tissues
of chronic rhinosinusitis (CRS) patients and reveal the relationship between CRS and …

Background None of current diagnostic methods has been proven to be a reliable tool for
gastro-esophageal reflux disease (GERD). Pepsin in saliva has been proposed as a …

Pepsin refluxate is considered a risk factor for laryngopharyngeal carcinogenesis. Non-
acidic pepsin was previously linked to an inflammatory and tumorigenic effect on …