SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants
D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …
Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health
Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …
remain numerous globally devastating diseases without fully protective vaccines, particularly …
Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications
YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need
remains for a globally available vaccine that provides longer-lasting immunity against …
remains for a globally available vaccine that provides longer-lasting immunity against …
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
MG Joyce, WH Chen, RS Sankhala, A Hajduczki… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
[HTML][HTML] Induction of potent neutralizing antibody responses by a designed protein nanoparticle vaccine for respiratory syncytial virus
Respiratory syncytial virus (RSV) is a worldwide public health concern for which no vaccine
is available. Elucidation of the prefusion structure of the RSV F glycoprotein and its …
is available. Elucidation of the prefusion structure of the RSV F glycoprotein and its …
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
PJM Brouwer, M Brinkkemper, P Maisonnasse… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …
A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice
The development of a safe and effective SARS-CoV-2 vaccine is a public health priority. We
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …
Challenges and developments in universal vaccine design against SARS-CoV-2 variants
F Zhao, X Zai, Z Zhang, J Xu, W Chen - npj Vaccines, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had
become a global concern because of its unexpectedly high pathogenicity and …
become a global concern because of its unexpectedly high pathogenicity and …
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
In vaccine design, antigens are often arrayed in a multivalent nanoparticle form, but in vivo
mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly …
mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly …