Breathing is a natural and necessary process for humans. At the same time, the respiratory
pace and frequency can vary so much, depending on the status of the subject. Specifically …

Abstract Hypoxia-inducible factors (HIF)-1 and HIF-2 are master regulators of oxygen
homeostasis that regulate the expression of thousands of genes in order to match O2 supply …

The pulmonary circulation responds to hypoxia with vasoconstriction, a mechanism that
helps to adapt to short-lived hypoxic episodes. When sustained, hypoxic pulmonary …

Patients with sickle cell anemia (SCA) experience cerebral metabolic stress with an increase
in oxygen extraction fraction (OEF) to compensate for reduced oxygen carrying capacity due …

In cardiomyocytes, regular activity of the Na, K-ATPase (NKA) and its Na/K pump activity is
essential for maintaining ion gradients, excitability, propagation of action potentials, electro …

Introduction: Coronary artery disease (CAD) is one of the most life-threatening
cardiovascular emergencies with high mortality and morbidity. Increasing evidence has …

With the high incidence of diabetes around the world, ischemic complications cause a
serious influence on people's production and living. Neovascularization plays a significant …

Objectives: To perform multiscale correlation analysis between quantitative texture feature
phenotypes of pre-biopsy biparametric MRI (bpMRI) and targeted sequence-based RNA …

Heart diseases are caused mainly by chronic oxygen insufficiency (hypoxia), leading to
damage and apoptosis of cardiomyocytes. Research into the regeneration of a damaged …

Background It is valuable to analyze the genome-wide association studies (GWAS) data for
a complex disease phenotype in the context of the protein–protein interaction (PPI) network …