Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
CS Constantinescu, N Farooqi… - British journal of …, 2011 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is the most commonly used
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
[HTML][HTML] Autoimmune disorders of the nervous system: pathophysiology, clinical features, and therapy
S Bhagavati - Frontiers in neurology, 2021 - frontiersin.org
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …
Axon‐myelin unit blistering as early event in MS normal appearing white matter
A Luchicchi, B Hart, I Frigerio, AM van Dam… - Annals of …, 2021 - Wiley Online Library
Objective Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative
disease of unknown etiology. Although the prevalent view regards a CD4+‐lymphocyte …
disease of unknown etiology. Although the prevalent view regards a CD4+‐lymphocyte …
Oxidative modifications in tissue pathology and autoimmune disease
ML Yang, HA Doyle, SG Clarke, KC Herold… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Various autoimmune syndromes are characterized by abnormalities found at
the level of tissues and cells, as well as by microenvironmental influences, such as reactive …
the level of tissues and cells, as well as by microenvironmental influences, such as reactive …
Viruses and multiple sclerosis: from mechanisms and pathways to translational research opportunities
AFA Mentis, E Dardiotis, N Grigoriadis, E Petinaki… - Molecular …, 2017 - Springer
Viruses are directly or indirectly implicated in multiple sclerosis (MS). Here, we review the
evidence on the virus-related pathophysiology of MS, introduce common experimental …
evidence on the virus-related pathophysiology of MS, introduce common experimental …
Lupus autoimmunity altered by cellular methylation metabolism
ML Yang, AJP Gee, RJ Gee, CI Zurita-Lopez… - …, 2013 - Taylor & Francis
Modifications of both DNA and protein by methylation are key factors in normal T and B cell
immune responses as well as in the development of autoimmune disease. For example, the …
immune responses as well as in the development of autoimmune disease. For example, the …
The primate autoimmune encephalomyelitis model; a bridge between mouse and man
BA 't Hart, Y van Kooyk, JJG Geurts… - Annals of clinical and …, 2015 - Wiley Online Library
Introduction Multiple sclerosis (MS) is an enigmatic autoimmune‐driven inflammatory/
demyelinating disease of the human central nervous system (CNS), affecting brain, spinal …
demyelinating disease of the human central nervous system (CNS), affecting brain, spinal …
Unravelling the T‐cell‐mediated autoimmune attack on CNS myelin in a new primate EAE model induced with MOG34–56 peptide in incomplete adjuvant
SA Jagessar, N Heijmans, ELA Blezer… - European journal of …, 2012 - Wiley Online Library
Induction of experimental autoimmune encephalomyelitis (EAE) has been documented in
common marmosets using peptide 34–56 from human myelin/oligodendrocyte glycoprotein …
common marmosets using peptide 34–56 from human myelin/oligodendrocyte glycoprotein …
Autoantigens: novel forms and presentation to the immune system
HA Doyle, ML Yang, MT Raycroft, RJ Gee… - Autoimmunity, 2014 - Taylor & Francis
It is clear that lupus autoimmunity is marked by a variety of abnormalities, including those
found at a macroscopic scale, cells and tissues, as well as more microenvironmental …
found at a macroscopic scale, cells and tissues, as well as more microenvironmental …
[HTML][HTML] Axonal transport deficits in multiple sclerosis: spiraling into the abyss
R van den Berg, CC Hoogenraad, RQ Hintzen - Acta neuropathologica, 2017 - Springer
The transport of mitochondria and other cellular components along the axonal microtubule
cytoskeleton plays an essential role in neuronal survival. Defects in this system have been …
cytoskeleton plays an essential role in neuronal survival. Defects in this system have been …