Aging of liver in its different diseases

T Radonjić, M Dukić, I Jovanović, M Zdravković… - International Journal of …, 2022 - mdpi.com
The proportion of elderly people in the world population is constantly increasing. With age,
the risk of numerous chronic diseases and their complications also rises. Research on the …

Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Potential role of polyphenolic flavonoids as senotherapeutic agents in degenerative diseases and geroprotection

KC Mbara, N Devnarain, PMO Owira - Pharmaceutical Medicine, 2022 - Springer
Cellular senescence, a hallmark of ageing, contributes to tissue or organ dysfunction and
the pathophysiology of diverse age-related diseases (ARD) by various mechanisms …

Effects of fisetin treatment on cellular senescence of various tissues and organs of old sheep

CA Huard, X Gao, ME Dey Hazra, RO Dey Hazra… - Antioxidants, 2023 - mdpi.com
Fisetin has been shown to be beneficial for brain injury and age-related brain disease via
different mechanisms. The purpose of this study was to determine the presence of senescent …

Identification and characterization of aging/senescence-induced genes in osteosarcoma and predicting clinical prognosis

Y Lv, L Wu, H Jian, C Zhang, Y Lou, Y Kang… - Frontiers in …, 2022 - frontiersin.org
Background Aging is an influential risk factor for progression of both degenerative and
oncological diseases of the bone. Osteosarcoma, considered the most common primary …

[HTML][HTML] Diverse roles of cellular senescence in skeletal muscle inflammation, regeneration, and therapeutics

Y Saito, TS Chikenji - Frontiers in Pharmacology, 2021 - frontiersin.org
Skeletal muscle undergoes vigorous tissue remodeling after injury. However, aging, chronic
inflammatory diseases, sarcopenia, and neuromuscular disorders cause muscle loss and …

An aging-related gene signature-based model for risk stratification and prognosis prediction in lung adenocarcinoma

Q Xu, Y Chen - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Aging is an inevitable time-dependent process associated with a gradual decline in many
physiological functions. Importantly, some studies have supported that aging may be …

[HTML][HTML] Towards AI-driven longevity research: an overview

N Marino, G Putignano, S Cappilli, E Chersoni… - Frontiers in …, 2023 - frontiersin.org
While in the past technology has mostly been utilized to store information about the
structural configuration of proteins and molecules for research and medical purposes …

Doxycycline attenuated ethanol-induced inflammaging in endothelial cells: implications in alcohol-mediated vascular diseases

X Li, D Khan, M Rana, D Hänggi, S Muhammad - Antioxidants, 2022 - mdpi.com
Excess alcohol consumption is a potential risk factor for cardiovascular diseases and is
linked to accelerated aging. Drug discovery to reduce toxic cellular events of alcohol is …

The emerging role of accelerated cellular senescence in periodontitis

R Aquino-Martinez - Journal of Dental Research, 2023 - journals.sagepub.com
Accelerated cellular senescence may be a crucial process for periodontitis progression
because it integrates the damaging effects of major periodontitis risk factors. Cellular …