Parkinson's disease (PD) is the most common movement disorder and the second most
prevalent neurodegenerative disease after Alzheimer's disease. Despite decades of …

Figure 1. Major immunological alterations observed during immunosenescence.......................
.................................................................................. 5 Figure 2. Features of the aging phenotype …

Komórka jajowa jest największą komórką u różnych gatunków ssaków, a kobiety pragnące
zajść w ciążę muszą się liczyć z zegarem biologicznym. Jest to ogromne wyzwanie, biorąc …

Background Bladder cancer (BLCA) is the most common malignancy of the urinary system.
Muscle-invasive BLCA (MIBC), which constitutes approximately 25% of all BLCA cases, is …

Obese breast cancer patients suffer a worse prognosis than their normoweight counterparts,
including increased risks of recurrence and mortality. While the causative mechanisms …

Background: Metastases and recurrence of ovarian cancer after surgery and chemotherapy
account for most cancer-related deaths, yet the mechanism underlying metastases and …

Background: Bladder cancer (BLCA) is the most common malignant tumor of the urinary
system. With the aging of the population, the incidence of bladder cancer is increasing year …

Cellular senescence is a state of stable cell cycle arrest triggered by internal and external
stressors. A major hallmark of senescent cells is the senescent associated secretory …

Aging is the result of the deterioration of the homeostatic systems (nervous, endocrine, and
immune systems), which preserve the organism's health. We propose that the age-related …

Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant inherited disorder
manifested by the inability to coordinate balance, gait, and speech. Some experimental …