Estrogen receptors and their implications in colorectal carcinogenesis

F Caiazza, EJ Ryan, G Doherty, DC Winter… - Frontiers in …, 2015 - frontiersin.org
Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate
intracellular signaling cascades that have important consequences for cellular behavior …

[HTML][HTML] Influence of estrogen in non-small cell lung cancer and its clinical implications

V Rodriguez-Lara… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Lung cancer (LC) is the leading cause of cancer death in men worldwide and has
significantly increased in women. Differences in non-small cell lung cancer (NSCLC) …

Role of sex hormones in lung cancer

N Fuentes, M Silva Rodriguez… - … Biology and Medicine, 2021 - journals.sagepub.com
Lung cancer represents the world's leading cause of cancer deaths. Sex differences in the
incidence and mortality rates for various types of lung cancers have been identified, but the …

Oleuropein is a natural inhibitor of PAI-1-mediated proliferation in human ER-/PR-breast cancer cells

EE Tzekaki, G Geromichalos, SN Lavrentiadou… - Breast Cancer Research …, 2021 - Springer
Purpose Elevated expression of PAI-1 has been widely linked with adverse outcomes in a
variety of human cancers, such as breast, gastric and ovarian cancers, rendering PAI-1 a …

Exploring estrogenic activity in lung cancer

BK Słowikowski, M Lianeri, PP Jagodziński - Molecular biology reports, 2017 - Springer
It is well known that a connection between xenobiotics inhalation, especially tobacco
combustion and Lung Cancer development is strongly significant and indisputable …

[HTML][HTML] Hormonal replacement therapy and the risk of lung cancer in women: an adaptive meta-analysis of cohort studies

JM Bae, EH Kim - Journal of Preventive Medicine and Public …, 2015 - ncbi.nlm.nih.gov
Objectives: Approximately 10% to 15% of lung cancer cases occur in never-smokers.
Hormonal factors have been suggested to lead to an elevated risk of lung cancer in women …

[HTML][HTML] LncRNAs are altered in lung squamous cell carcinoma and lung adenocarcinoma

B Liu, Y Chen, J Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have been implicated in pathogenesis of various
cancers, including lung squamous cell carcinoma (LUSC) and lung adenocarcinoma …

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer

YS Brooks, P Ostano, SH Jo, J Dai… - The Journal of …, 2014 - Am Soc Clin Investig
Downmodulation or loss-of-function mutations of the gene encoding NOTCH1 are
associated with dysfunctional squamous cell differentiation and development of squamous …

Smoking, sex, and non–small cell lung cancer: Steroid hormone receptors in tumor tissue (S0424)

TYD Cheng, AK Darke, MW Redman… - JNCI: Journal of the …, 2018 - academic.oup.com
Background To what extent steroid hormones contribute to lung cancer in male and female
never smokers and smokers is unclear. We examined expression of hormone receptors in …

Application of two-dimensional difference gel electrophoresis to identify protein changes between center, margin, and adjacent non-tumor tissues obtained from non …

A Ciereszko, MA Dietrich, M Słowińska, J Nynca… - Plos one, 2022 - journals.plos.org
Lung cancer is responsible for the most cancer-related mortality worldwide and the
mechanism of its development is poorly understood. Proteomics has become a powerful tool …