Are “mystical experiences” essential for antidepressant actions of ketamine and the classic psychedelics?

K Hashimoto - European Archives of Psychiatry and Clinical …, 2024 - Springer
The growing interest in the rapid and sustained antidepressant effects of the dissociative
anesthetic ketamine and classic psychedelics, such as psilocybin, is remarkable. However …

Efficacy and safety of esketamine for perioperative depression in patients undergoing elective surgery: A meta-analysis of randomized controlled trials

X Lou, D Qiu, Z Ren, K Hashimoto, G Zhang… - Asian journal of …, 2024 - Elsevier
Background Depression is a prevalent mood disorder during the perioperative period, with
both preoperative concurrent depression and new-onset postoperative depression …

[HTML][HTML] Clinical characteristics and treatment exposure of patients with marked treatment-resistant unipolar major depressive disorder: A RECOVER trial report

CR Conway, ST Aaronson, HA Sackeim, W Duffy… - Brain stimulation, 2024 - Elsevier
Background RECOVER is a randomized sham-controlled trial of vagus nerve stimulation
and the largest such trial conducted with a psychiatric neuromodulation intervention …

[HTML][HTML] Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions

K Hashimoto, M Zhao, T Zhu, X Wang, J Yang - Journal of Anesthesia and …, 2024 - Elsevier
Ketamine, a dissociative anesthetic, is widely utilized in both human and veterinary
anesthesia. Its (S)-enantiomer, esketamine, is similarly employed for anesthesia and …

The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway

J Wang, Y Feng, Z Qi, J Li, Z Chen, J Zhang… - Open Life …, 2024 - degruyter.com
Remifentanil-induced hyperalgesia (RIH) is a common clinical phenomenon that limits the
use of opioids in pain management. Esketamine, a non-competitive N-methyl-d-aspartate …

[PDF][PDF] Cetamina: um psicadélico em ascensão na depressão resistente ao tratamento

PE da Silva Santos - 2024 - repositorio-aberto.up.pt
Introdução: A depressão afeta mais de 300 milhões de pessoas. Cerca de 30% dos
indivíduos não apresenta resposta clínica à terapêutica antidepressiva, condição designada …

Leserbrief zu: Ketamininfusionstherapie zur Behandlung von Depressionen–Schritt für Schritt

U Bonnet - PSYCH up2date, 2024 - thieme-connect.com
Schritt “in der PSYCH up2date gelesen [1]. Die Arbeit enthält viele sehr brauchbare Tipps,
meiner Meinung nach jedoch auch einige Aussagen und Empfehlungen, die …

Antwort zum Leserbrief: Ketamininfusionstherapie zur Behandlung von Depressionen–Schritt für Schritt

F Müller-Dahlhaus, M Junginger, W Kelsch - PSYCH up2date, 2024 - thieme-connect.com
In der Tat weist eine Anfang dieses Jahres erschienene Netzwerk-Metaanalyse nicht nur auf
eine überlegene Wirksamkeit, sondern auch auf eine überlegene Verträglichkeit …