A review of disintegration mechanisms and measurement techniques

D Markl, JA Zeitler - Pharmaceutical research, 2017 - Springer
Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …

Pharmaceutical applications of cellulose ethers and cellulose ether esters

HC Arca, LI Mosquera-Giraldo, V Bi, D Xu… - …, 2018 - ACS Publications
Cellulose ethers have proven to be highly useful natural-based polymers, finding application
in areas including food, personal care products, oil field chemicals, construction, paper …

Fast time-resolved micro-CT imaging of pharmaceutical tablets: Insights into water uptake and disintegration

S Ferdoush, SB Kzam, PHC Martins… - International journal of …, 2023 - Elsevier
We use dynamic micro-computed tomography (micro-CT) with a high temporal resolution to
visualize water penetration through the porous network of immediate-release …

Advanced material applications of starch and its derivatives

E Ogunsona, E Ojogbo, T Mekonnen - European Polymer Journal, 2018 - Elsevier
Starch as a natural polymer has attracted significant interest and is currently used in
numerous industrial applications. This is because of its renewability, biodegradability …

Pharmaceutical and biomedical applications of native and modified starch: a review

MAVT Garcia, CF Garcia, AAG Faraco - Starch‐Stärke, 2020 - Wiley Online Library
Starch is a natural, renewable, and biodegradable polymer produced by many plants as a
source of stored energy. The structural and functional diversity of starches makes them …

Characterisation of pore structures of pharmaceutical tablets: A review

D Markl, A Strobel, R Schlossnikl, J Bøtker… - International journal of …, 2018 - Elsevier
Traditionally, the development of a new solid dosage form is formulation-driven and less
focus is put on the design of a specific microstructure for the drug delivery system. However …

Orally disintegrating tablets and orally disintegrating mini tablets–novel dosage forms for pediatric use

T Comoglu, E Dilek Ozyilmaz - Pharmaceutical Development and …, 2019 - Taylor & Francis
The oral administration route is considered to be the most widely used route because of its
convenience of administration and manufacturing. Dosage forms, like orally disintegrating …

Directly compressed tablets: A novel drug‐containing reservoir combined with hydrogel‐forming microneedle arrays for transdermal drug delivery

E McAlister, B Dutton, LK Vora, L Zhao… - Advanced …, 2021 - Wiley Online Library
Microneedle (MN) patches consist of a hydrogel‐forming MN array and a drug‐containing
reservoir. Drug‐containing reservoirs documented in the literature include polymeric films …

Advancing the understanding of the tablet disintegration phenomenon–an update on recent studies

A Berardi, L Bisharat, J Quodbach, SA Rahim… - International Journal of …, 2021 - Elsevier
Disintegration is the de-aggregation of particles within tablets upon exposure to aqueous
fluids. Being an essential step in the bioavailability cascade, disintegration is a fundamental …

Excipient stability in oral solid dosage forms: a review

MA Darji, RM Lalge, SP Marathe, TD Mulay, T Fatima… - Aaps Pharmscitech, 2018 - Springer
The choice of excipients constitutes a major part of preformulation and formulation studies
during the preparation of pharmaceutical dosage forms. The physical, mechanical, and …