Biodegradable polyurethane scaffolds in regenerative medicine: Clinical translation review

DD Pedersen, S Kim… - Journal of Biomedical …, 2022 - Wiley Online Library
Early explorations of tissue engineering and regenerative medicine concepts commonly
utilized simple polyesters such as polyglycolide, polylactide, and their copolymers as …

[HTML][HTML] Innervation: the missing link for biofabricated tissues and organs

S Das, WJ Gordián-Vélez, HC Ledebur… - NPJ Regenerative …, 2020 - nature.com
Innervation plays a pivotal role as a driver of tissue and organ development as well as a
means for their functional control and modulation. Therefore, innervation should be carefully …

[PDF][PDF] Dysregulation of BRD4 function underlies the functional abnormalities of MeCP2 mutant neurons

Y Xiang, Y Tanaka, B Patterson, SM Hwang, E Hysolli… - Molecular cell, 2020 - cell.com
Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …

[HTML][HTML] Porcine Small Intestinal Submucosa (SIS) as a Suitable scaffold for the creation of a tissue-engineered urinary conduit: Decellularization, biomechanical and …

M Casarin, TM Fortunato, S Imran, M Todesco… - International journal of …, 2022 - mdpi.com
Bladder cancer (BC) is among the most common malignancies in the world and a relevant
cause of cancer mortality. BC is one of the most frequent causes for bladder removal through …

Biomaterials assisted reconstructive urology: The pursuit of an implantable bioengineered neo-urinary bladder

S Sharma, B Basu - Biomaterials, 2022 - Elsevier
Urinary bladder is a dynamic organ performing complex physiological activities. Together
with ureters and urethra, it forms the lower urinary tract that facilitates urine collection, low …

[HTML][HTML] The significance of biomechanics and scaffold structure for bladder tissue engineering

M Hanczar, M Moazen, R Day - International Journal of Molecular …, 2021 - mdpi.com
Current approaches for bladder reconstruction surgery are associated with many
morbidities. Tissue engineering is considered an ideal approach to create constructs …

Hydraulic detrusor for artificial bladder active voiding

G Casagrande, M Ibrahimi, F Semproni, V Iacovacci… - Soft …, 2023 - liebertpub.com
The gold standard treatment for bladder cancer is radical cystectomy that implies bladder
removal coupled to urinary diversions. Despite the serious complications and the …

Review of clinical experience on biomaterials and tissue engineering of urinary bladder

ME Chua, WA Farhat, JM Ming, KA McCammon - World Journal of Urology, 2020 - Springer
Purpose In recent pre-clinical studies, biomaterials and bladder tissue engineering have
shown promising outcomes when addressing the need for bladder tissue replacement. To …

[HTML][HTML] Current applications and future directions of bioengineering approaches for bladder augmentation and reconstruction

X Wang, F Zhang, L Liao - Frontiers in Surgery, 2021 - frontiersin.org
End-stage neurogenic bladder usually results in the insufficiency of upper urinary tract,
requiring bladder augmentation with intestinal tissue. To avoid complications of …

Reconstructive urology and tissue engineering: Converging developmental paths

J Adamowicz, B Kuffel, SV Van Breda… - Journal of tissue …, 2019 - Wiley Online Library
Reconstructive urology is a complex and demanding branch of modern urology.
Complicated cases, necessity of microsurgical approach, and constant exposure to urine …