The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

A Idnurm, YS Bahn, K Nielsen, X Lin… - Nature Reviews …, 2005 - nature.com
Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

SreA‐mediated iron regulation in Aspergillus fumigatus

M Schrettl, HS Kim, M Eisendle, C Kragl… - Molecular …, 2008 - Wiley Online Library
Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two
high‐affinity iron uptake systems: iron uptake mediated by the extracellular siderophore …

[HTML][HTML] Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

TR O'Meara, D Norton, MS Price, C Hay… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues in order to establish a human infection. We have identified the C …

[HTML][HTML] SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus

M Blatzer, BM Barker, SD Willger, N Beckmann… - PLoS …, 2011 - journals.plos.org
Sterol regulatory element binding proteins (SREBPs) are a class of basic helix-loop-helix
transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the …

[HTML][HTML] Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans

WH Jung, A Sham, R White, JW Kronstad - PLoS biology, 2006 - journals.plos.org
Iron overload is known to exacerbate many infectious diseases, and conversely, iron
withholding is an important defense strategy for mammalian hosts. Iron is a critical cue for …

Cryptococcus neoformans Gene Expression during Murine Macrophage Infection

W Fan, PR Kraus, MJ Boily, J Heitman - Eukaryotic cell, 2005 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans survives phagocytosis by macrophages and
proliferates within, ultimately establishing latent infection as a facultative intracellular …

[HTML][HTML] Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals

N Trevijano-Contador, HC de Oliveira… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of
the cells during infection. In particular, this process can occur by enlarging the size of the …